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Serving hundreds of leading biopharmaceutical companies globally:

Fish and Richardson
Chubb
UBS
QuintilesIMS
Baxter
Express Scripts
Covington
AstraZeneca
Merck

Generated: December 14, 2018

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CLINICAL TRIALS PROFILE FOR COSOPT

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Clinical Trials for Cosopt

Trial ID Title Status Sponsor Phase Summary
NCT00140049 A 12week, Randomized, Evaluator-Masked, Parallel Group Comparing Evening Dosing Of Xalacom Vs Cosopt In Subj W/ Glaucoma Completed Pfizer Phase 4 To demonstrate the statistical non inferiority of the combination of latanoprost and timolol given in the evening time once a day vs the combination of dorzamalide and timolol twice a day based on intraocular pressure measurements at 8 AM, 12 noon & 4 PM during a 12 week treatment.
NCT00273429 Cosopt Versus Xalatan Completed Pharmaceutical Research Network Phase 4 To compare the 24-hour efficacy and safety, measured every three hours, of the dorzolamide/timolol fixed combination given twice daily versus latanoprost and placebo each given once daily.
NCT00273442 Assessing Cosopt Switch Patients Completed Pharmaceutical Research Network Phase 4 To assess the safety and efficacy of a cohort of patients switched to the dorzolamide/timolol maleate fixed combination because they are insufficiently controlled on latanoprost monotherapy.
NCT00273455 Lumigan Versus Cosopt Completed Pharmaceutical Research Network Phase 4 To compare the intraocular pressure effect and safety of the dorzolamide/timolol fixed combination given twice daily versus bimatoprost given once every evening in patients with open-angle glaucoma in patients insufficiently controlled on latanoprost monotherapy
NCT00273481 Cosopt Versus Xalacom Completed Pharmaceutical Research Network Phase 4 To compare the intraocular pressure efficacy and safety of the DTFC given twice daily versus the LTFC given once every morning following a run-in period with timolol maleate given twice daily.
NCT00314171 A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension Completed Alcon Research Phase 3 The purpose of this study is to determine whether a glaucoma therapy is safe and effective in treating patients with open-angle glaucoma or ocular hypertension.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Cosopt

Condition Name

Condition Name for Cosopt
Intervention Trials
Ocular Hypertension 18
Glaucoma 15
Open-angle Glaucoma 10
Open Angle Glaucoma 2
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Condition MeSH

Condition MeSH for Cosopt
Intervention Trials
Glaucoma 25
Ocular Hypertension 19
Glaucoma, Open-Angle 15
Hypertension 14
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Clinical Trial Locations for Cosopt

Trials by Country

Trials by Country for Cosopt
Location Trials
United States 24
Canada 4
Greece 3
Italy 2
Mexico 2
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Trials by US State

Trials by US State for Cosopt
Location Trials
Pennsylvania 3
Massachusetts 3
Texas 2
South Carolina 2
Illinois 2
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Clinical Trial Progress for Cosopt

Clinical Trial Phase

Clinical Trial Phase for Cosopt
Clinical Trial Phase Trials
Phase 4 17
Phase 3 5
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Cosopt
Clinical Trial Phase Trials
Completed 25
Unknown status 4
Terminated 2
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Clinical Trial Sponsors for Cosopt

Sponsor Name

Sponsor Name for Cosopt
Sponsor Trials
Alcon Research 8
Merck Sharp & Dohme Corp. 6
Pharmaceutical Research Network 4
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Sponsor Type

Sponsor Type for Cosopt
Sponsor Trials
Other 25
Industry 21
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Serving hundreds of leading biopharmaceutical companies globally:

Julphar
Medtronic
Daiichi Sankyo
Federal Trade Commission
UBS
Fish and Richardson
Accenture
McKesson
McKinsey

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