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Last Updated: January 27, 2023

CLINICAL TRIALS PROFILE FOR CLINORIL


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All Clinical Trials for Clinoril

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00005882 ↗ Eflornithine and Sulindac in Preventing Colorectal Cancer in Patients With Colon Polyps Completed Chao Family Comprehensive Cancer Center Phase 3 1998-07-01 This randomized phase III trial is studying eflornithine and sulindac to see how well they work compared to a placebo in preventing colorectal cancer in patients with colon polyps. Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of eflornithine and sulindac may prevent colorectal cancer. It is not yet known whether eflornithine and sulindac are more effective than a placebo in preventing colorectal cancer
NCT00005882 ↗ Eflornithine and Sulindac in Preventing Colorectal Cancer in Patients With Colon Polyps Completed National Cancer Institute (NCI) Phase 3 1998-07-01 This randomized phase III trial is studying eflornithine and sulindac to see how well they work compared to a placebo in preventing colorectal cancer in patients with colon polyps. Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of eflornithine and sulindac may prevent colorectal cancer. It is not yet known whether eflornithine and sulindac are more effective than a placebo in preventing colorectal cancer
NCT00005882 ↗ Eflornithine and Sulindac in Preventing Colorectal Cancer in Patients With Colon Polyps Completed University of California, Irvine Phase 3 1998-07-01 This randomized phase III trial is studying eflornithine and sulindac to see how well they work compared to a placebo in preventing colorectal cancer in patients with colon polyps. Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of eflornithine and sulindac may prevent colorectal cancer. It is not yet known whether eflornithine and sulindac are more effective than a placebo in preventing colorectal cancer
NCT00062023 ↗ Comparison of Sulindac, Aspirin, and Ursodiol in Preventing Colorectal Cancer Terminated National Cancer Institute (NCI) Phase 2 2003-06-01 RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. It is not yet known whether sulindac, aspirin, or ursodiol is more effective in preventing colorectal cancer. PURPOSE: This randomized phase II trial is studying how well sulindac works compared to aspirin or ursodiol in preventing colorectal cancer.
NCT00062023 ↗ Comparison of Sulindac, Aspirin, and Ursodiol in Preventing Colorectal Cancer Terminated M.D. Anderson Cancer Center Phase 2 2003-06-01 RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. It is not yet known whether sulindac, aspirin, or ursodiol is more effective in preventing colorectal cancer. PURPOSE: This randomized phase II trial is studying how well sulindac works compared to aspirin or ursodiol in preventing colorectal cancer.
NCT00068419 ↗ Sulindac and Tamoxifen in Treating Patients With Desmoid Tumor Completed National Cancer Institute (NCI) Phase 2 2004-02-01 This phase II trial is studying how well giving sulindac together with tamoxifen works in treating patients with desmoid tumor. Sulindac may stop the growth of cancer cells by blocking the enzymes necessary for cancer cell growth. Hormone therapy using tamoxifen may fight cancer by blocking the use of estrogen. Combining sulindac with tamoxifen may kill more cancer cells.
NCT00068419 ↗ Sulindac and Tamoxifen in Treating Patients With Desmoid Tumor Completed Children's Oncology Group Phase 2 2004-02-01 This phase II trial is studying how well giving sulindac together with tamoxifen works in treating patients with desmoid tumor. Sulindac may stop the growth of cancer cells by blocking the enzymes necessary for cancer cell growth. Hormone therapy using tamoxifen may fight cancer by blocking the use of estrogen. Combining sulindac with tamoxifen may kill more cancer cells.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Clinoril

Condition Name

Condition Name for Clinoril
Intervention Trials
Precancerous Condition 5
Colorectal Cancer 2
Rectal Cancer 1
Stage I Non-small Cell Lung Cancer 1
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Condition MeSH

Condition MeSH for Clinoril
Intervention Trials
Precancerous Conditions 5
Colorectal Neoplasms 3
Nasopharyngeal Neoplasms 1
Fibromatosis, Aggressive 1
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Clinical Trial Locations for Clinoril

Trials by Country

Trials by Country for Clinoril
Location Trials
United States 30
Canada 2
United Kingdom 2
Netherlands 1
Germany 1
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Trials by US State

Trials by US State for Clinoril
Location Trials
California 5
Arizona 4
Minnesota 3
Ohio 2
Massachusetts 2
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Clinical Trial Progress for Clinoril

Clinical Trial Phase

Clinical Trial Phase for Clinoril
Clinical Trial Phase Trials
Phase 3 3
Phase 2 6
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Clinical Trial Status

Clinical Trial Status for Clinoril
Clinical Trial Phase Trials
Completed 7
Terminated 1
Unknown status 1
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Clinical Trial Sponsors for Clinoril

Sponsor Name

Sponsor Name for Clinoril
Sponsor Trials
National Cancer Institute (NCI) 8
Chao Family Comprehensive Cancer Center 1
University of California, Irvine 1
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Sponsor Type

Sponsor Type for Clinoril
Sponsor Trials
NIH 8
Other 5
Industry 1
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Serving leading biopharmaceutical companies globally:

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Dow

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