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Last Updated: May 26, 2022

CLINICAL TRIALS PROFILE FOR CIMETIDINE HYDROCHLORIDE


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All Clinical Trials for Cimetidine Hydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00002092 ↗ A Study to Evaluate the Effect of Cimetidine on CD4 Lymphocyte Counts in HIV Infection Completed Community Research Initiative of New England N/A 1969-12-31 To determine the change in CD4 count after 4 and 8 weeks in HIV-infected patients treated with cimetidine compared to placebo. To observe time-associated trends at weeks 4, 8, 12, and 16 in the change of CD4 counts for patients taking cimetidine for the full 16 weeks. To establish a safety record for cimetidine use in HIV-positive patients.
NCT00002733 ↗ Biological Therapy in Treating Patients With Metastatic Cancer Completed Hoag Memorial Hospital Presbyterian Phase 2 1996-01-01 RATIONALE: Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing. Combining different types of biological therapies, including interferon alfa, interleukin-2, and tumor infiltrating lymphocytes, may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of biological therapies, including interferon alfa, interleukin-2, and tumor infiltrating lymphocytes, in treating patients with metastatic cancer.
NCT00038402 ↗ Evaluation of the Addition of Herceptin to Standard Chemotherapy in the Neoadjuvant Setting for Operable Breast Cancer Completed Genentech, Inc. Phase 3 2001-04-01 The purpose of this study is to evaluate the addition of Herceptin to standard chemotherapy treatment of patients newly diagnosed with operable breast cancer. Other objectives: 1) to evaluate the potential of this therapy to reduce the size of the tumor and increase the possibility of breast conservative surgery, 2) evaluate the ability of this regimen to prevent recurrence of breast cancer and impact on survival, 3) determine side effect profile with the addition of Herceptin, and 4) evaluate significance of HER2 expression by two different methods.
NCT00038402 ↗ Evaluation of the Addition of Herceptin to Standard Chemotherapy in the Neoadjuvant Setting for Operable Breast Cancer Completed M.D. Anderson Cancer Center Phase 3 2001-04-01 The purpose of this study is to evaluate the addition of Herceptin to standard chemotherapy treatment of patients newly diagnosed with operable breast cancer. Other objectives: 1) to evaluate the potential of this therapy to reduce the size of the tumor and increase the possibility of breast conservative surgery, 2) evaluate the ability of this regimen to prevent recurrence of breast cancer and impact on survival, 3) determine side effect profile with the addition of Herceptin, and 4) evaluate significance of HER2 expression by two different methods.
NCT00045799 ↗ Safety & Efficacy of Omeprazole Sodium Bicarbonate for the Prevention of Upper GI Bleeding in the Critically Ill Completed Bausch Health Americas, Inc. Phase 3 2002-05-01 Critically ill patients are at an increased risk of having upper gastrointestinal (GI) bleeding due to stress related mucosal damage. Cimetidine, delivered continuously through intravenous infusion, is the only drug that the FDA has approved for the prevention of upper GI bleeding in critically ill patients. The present trial is intended to assess the safety and efficacy of an omeprazole sodium bicarbonate immediate-release suspension in this indication.
NCT00045799 ↗ Safety & Efficacy of Omeprazole Sodium Bicarbonate for the Prevention of Upper GI Bleeding in the Critically Ill Completed Valeant Pharmaceuticals International, Inc. Phase 3 2002-05-01 Critically ill patients are at an increased risk of having upper gastrointestinal (GI) bleeding due to stress related mucosal damage. Cimetidine, delivered continuously through intravenous infusion, is the only drug that the FDA has approved for the prevention of upper GI bleeding in critically ill patients. The present trial is intended to assess the safety and efficacy of an omeprazole sodium bicarbonate immediate-release suspension in this indication.
NCT00050167 ↗ Evaluation of Differing Taxanes/Taxane Combinations on the Outcome of Patients With Operable Breast Cancer Completed Roche Pharma AG Phase 1 2002-11-01 Primary Objectives: - Determine the impact of each regimen on the disease free and overall survival of patients with operable breast cancer. - Determine the ability of docetaxel/capecitabine to downstage primary breast cancer when administered in the neoadjuvant setting when compared with weekly paclitaxel. - Determine the ability of each regimen to enhance breast conservation therapy when administered in the neoadjuvant setting. (See protocol text for additional objectives and details).
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Cimetidine Hydrochloride

Condition Name

Condition Name for Cimetidine Hydrochloride
Intervention Trials
Healthy 5
Rectal Cancer 2
Breast Cancer 2
Gastric Cancer 2
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Condition MeSH

Condition MeSH for Cimetidine Hydrochloride
Intervention Trials
Breast Neoplasms 3
Carcinoma 3
Infections 3
Gastroesophageal Reflux 2
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Clinical Trial Locations for Cimetidine Hydrochloride

Trials by Country

Trials by Country for Cimetidine Hydrochloride
Location Trials
United States 83
China 5
Germany 5
France 2
Ireland 2
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Trials by US State

Trials by US State for Cimetidine Hydrochloride
Location Trials
Texas 13
Massachusetts 4
Florida 4
California 3
Pennsylvania 3
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Clinical Trial Progress for Cimetidine Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Cimetidine Hydrochloride
Clinical Trial Phase Trials
Phase 4 8
Phase 3 10
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Cimetidine Hydrochloride
Clinical Trial Phase Trials
Completed 34
Unknown status 12
Recruiting 5
[disabled in preview] 8
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Clinical Trial Sponsors for Cimetidine Hydrochloride

Sponsor Name

Sponsor Name for Cimetidine Hydrochloride
Sponsor Trials
M.D. Anderson Cancer Center 9
Genentech, Inc. 4
Assiut University 3
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Sponsor Type

Sponsor Type for Cimetidine Hydrochloride
Sponsor Trials
Other 56
Industry 32
NIH 3
[disabled in preview] 2
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