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Generated: February 18, 2019

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CLINICAL TRIALS PROFILE FOR CHLORZOXAZONE

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Clinical Trials for Chlorzoxazone

Trial ID Title Status Sponsor Phase Summary
NCT00330434 Effect of Ethanol and Genetic Polymorphisms on Bupropion Metabolism Completed National Institute on Alcohol Abuse and Alcoholism (NIAAA) N/A The two purposes of this study are 1. to determine what effect the chronic and moderate/heavy drinking of alcoholic beverages has 1. on the blood level of bupropion and chlorzoxazone and their major breakdown products in the blood and 2. on the stimulant effect of bupropion and 2. to determine what effect a normal and common (25% frequency) genetic variation of a specific liver enzyme (that breaks down bupropion) has 1. on the blood levels of bupropion and its major breakdown products in the blood and 2. on the stimulant effect of bupropion. Two groups of volunteers will be recruited for this study: 1. volunteers who drink moderate to heavy amounts of alcohol frequently and 2. volunteers who usually do not drink alcohol. Volunteers will NOT be asked to change their drinking (or nondrinking) habits during the study.
NCT01187862 Pharmacokinetic Study to Investigate Low-dose Combinations of a Cocktail of Seven Drugs for Simultaneous Phenotyping of Cytochromes Completed University Hospital, Basel, Switzerland Phase 1 The purpose of this study is to assess whether a cocktail of seven approved drugs (so-called "Basel cocktail") can be used for simultaneous phenotyping of CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP2E1 and CYP3A4.
NCT01342341 Placebo-Controlled Cross Over Trial of Chlorzoxazone Intake Completed University of California, San Francisco Phase 4 The overall goals of this study are to (1) expand knowledge about interactions of chlorzoxazone with alcohol by assessing the effects of chlorzoxazone compared to placebo in moderate and heavy social alcohol users and (2) to compare the effects of chlorzoxazone on visual cue induced alcohol craving to placebo in moderate to heavy social alcohol users.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Chlorzoxazone

Condition Name

Condition Name for Chlorzoxazone
Intervention Trials
Pharmacokinetics 1
Alcohol Abuse 1
Cytochrome 1
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Condition MeSH

Condition MeSH for Chlorzoxazone
Intervention Trials
Breast Neoplasms 1
Depression 1
Osteoarthritis, Knee 1
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Clinical Trial Locations for Chlorzoxazone

Trials by Country

Trials by Country for Chlorzoxazone
Location Trials
United States 2
Denmark 2
Switzerland 1
Germany 1
Canada 1
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Trials by US State

Trials by US State for Chlorzoxazone
Location Trials
California 1
Massachusetts 1
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Clinical Trial Progress for Chlorzoxazone

Clinical Trial Phase

Clinical Trial Phase for Chlorzoxazone
Clinical Trial Phase Trials
Phase 4 4
Phase 2 1
Phase 1 2
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Clinical Trial Status

Clinical Trial Status for Chlorzoxazone
Clinical Trial Phase Trials
Completed 5
Recruiting 3
Enrolling by invitation 1
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Clinical Trial Sponsors for Chlorzoxazone

Sponsor Name

Sponsor Name for Chlorzoxazone
Sponsor Trials
Swedish Orphan Biovitrum 1
Kuopio University Hospital 1
University of California, San Francisco 1
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Sponsor Type

Sponsor Type for Chlorzoxazone
Sponsor Trials
Other 14
Industry 2
NIH 1
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Serving hundreds of leading biopharmaceutical companies globally:

Cerilliant
Mallinckrodt
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Teva
Chinese Patent Office
Covington
US Department of Justice
Harvard Business School
Farmers Insurance

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