CLINICAL TRIALS PROFILE FOR CEVIMELINE

All Clinical Trials for Cevimeline

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00017511 ↗	Cevimeline in Treating Patients With Dry Mouth Caused by Radiation Therapy for Head and Neck Cancer	Completed	Daiichi Sankyo Inc.	Phase 3	2001-06-01	RATIONALE: Cevimeline may be effective in treating dry mouth that is caused by radiation therapy for head and neck cancer. It is not yet known if cevimeline is more effective than no therapy in treating dry mouth caused by radiation therapy. PURPOSE: Randomized phase III trial to determine the effectiveness of cevimeline in treating patients who have dryness of the mouth caused by radiation therapy for head and neck cancer.
NCT00017511 ↗	Cevimeline in Treating Patients With Dry Mouth Caused by Radiation Therapy for Head and Neck Cancer	Completed	Daiichi Sankyo, Inc.	Phase 3	2001-06-01	RATIONALE: Cevimeline may be effective in treating dry mouth that is caused by radiation therapy for head and neck cancer. It is not yet known if cevimeline is more effective than no therapy in treating dry mouth caused by radiation therapy. PURPOSE: Randomized phase III trial to determine the effectiveness of cevimeline in treating patients who have dryness of the mouth caused by radiation therapy for head and neck cancer.
NCT00466388 ↗	Study of the Effectiveness of Cevimeline on Oral Health in Patients With Radiation Induced Xerostomia	Completed	Duke University	Phase 4	2007-05-01	The purpose of this study is to determine the effectiveness of cevimeline (versus placebo) on the oral health of patients who have dry mouth which was caused by radiation therapy that was given for treatment of head and/or neck cancer.
NCT00466388 ↗	Study of the Effectiveness of Cevimeline on Oral Health in Patients With Radiation Induced Xerostomia	Completed	American Academy of Otolaryngology-Head and Neck Surgery Foundation	Phase 4	2007-05-01	The purpose of this study is to determine the effectiveness of cevimeline (versus placebo) on the oral health of patients who have dry mouth which was caused by radiation therapy that was given for treatment of head and/or neck cancer.
NCT01690052 ↗	Efficacy of Cevimeline Versus Pilocarpine in the Secretion of Saliva	Completed	University of Kentucky	N/A	2009-01-01	The main objectives were: 1) To determine the efficacy of both cevimeline and pilocarpine in the secretion of saliva in patients with xerostomia, and 2) To compare the side-effects between the treatment for xerostomia with cevimeline and with pilocarpine.

Clinical Trial Conditions for Cevimeline

Condition Name

Condition Name for Cevimeline
Intervention	Trials
Dry Mouth	3
Head and Neck Cancer	1
Oral Complications	1
Overactive Bladder Syndrome	1

Condition MeSH

Condition MeSH for Cevimeline
Intervention	Trials
Xerostomia	4
Urinary Bladder, Overactive	1
Syndrome	1
Sjogren's Syndrome	1

Clinical Trial Locations for Cevimeline

Trials by Country

Trials by Country for Cevimeline
Location	Trials
United States	43
Taiwan	1

Trials by US State

Trials by US State for Cevimeline
Location	Trials
Kentucky	3
Kansas	2
Illinois	2
Colorado	2
Nevada	2

Clinical Trial Progress for Cevimeline

Clinical Trial Phase

Clinical Trial Phase for Cevimeline
Clinical Trial Phase	Trials
Phase 4	2
Phase 3	1
N/A	1

Clinical Trial Status

Clinical Trial Status for Cevimeline
Clinical Trial Phase	Trials
Completed	5
Recruiting	1

Clinical Trial Sponsors for Cevimeline

Sponsor Name

Sponsor Name for Cevimeline
Sponsor	Trials
Roxane Laboratories	2
American Academy of Otolaryngology-Head and Neck Surgery Foundation	1
University of Kentucky	1

Sponsor Type

Sponsor Type for Cevimeline
Sponsor	Trials
Other	4
Industry	4