Antibiotics for Postpartum Third and Fourth Degree Perineal Tear Repairs
Completed
Santa Clara Valley Health & Hospital System
N/A
2003-09-01
This study is undertaken to find out whether prophylactic antibiotics can decrease the
infection rate in third and fourth degree perineal tear repairs done in the immediate
postpartum period.
Antibiotics for Postpartum Third and Fourth Degree Perineal Tear Repairs
Completed
Stanford University
N/A
2003-09-01
This study is undertaken to find out whether prophylactic antibiotics can decrease the
infection rate in third and fourth degree perineal tear repairs done in the immediate
postpartum period.
Prophylactic Intrapartum Antibiotics and Immunological Markers for Postpartum Morbidity in HIV Positive Women
Completed
Bristol-Myers Squibb
N/A
2003-02-01
Postpartum infections are among the leading causes of maternal mortality world-wide,
particularly in under-resourced countries. Available data suggests that HIV infected women
are at greater risk of postpartum complications than uninfected women. In South Africa,
HIV/AIDS and related infections are now cumulatively the leading causes of maternal deaths
(though indirectly), with puerperal sepsis among the 5 most common causes.
This was a prospective longitudinal cohort of HIV infected (n = 675) and uninfected (n = 648)
women. These were women in whom vaginal delivery was anticipated, and were recruited at > 36
weeks of gestation during the antenatal period.
Hypothesis - HIV infected women are at increased risk of postpartum infectious morbidity and
this morbidity can be reduced by use of prophylactic intrapartum antibiotics.
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