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Last Updated: March 19, 2024

CLINICAL TRIALS PROFILE FOR CASPOFUNGIN ACETATE


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All Clinical Trials for Caspofungin Acetate

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00008359 ↗ Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed National Cancer Institute (NCI) Phase 3 2000-08-01 RATIONALE: Caspofungin acetate or amphotericin B liposomal may be effective in preventing or controlling fever and neutropenia caused by chemotherapy, bone marrow transplantation, or peripheral stem cell transplantation. It is not yet known whether caspofungin acetate or amphotericin B liposomal is more effective for treating these side effects. PURPOSE: Randomized phase III trial to compare the effectiveness of caspofungin acetate with that of amphotericin B liposomal in treating patients who have persistent fever and neutropenia after receiving anticancer therapy.
NCT00008359 ↗ Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed Memorial Sloan Kettering Cancer Center Phase 3 2000-08-01 RATIONALE: Caspofungin acetate or amphotericin B liposomal may be effective in preventing or controlling fever and neutropenia caused by chemotherapy, bone marrow transplantation, or peripheral stem cell transplantation. It is not yet known whether caspofungin acetate or amphotericin B liposomal is more effective for treating these side effects. PURPOSE: Randomized phase III trial to compare the effectiveness of caspofungin acetate with that of amphotericin B liposomal in treating patients who have persistent fever and neutropenia after receiving anticancer therapy.
NCT00020527 ↗ Caspofungin Acetate in Treating Children With Fever and Neutropenia Completed National Cancer Institute (NCI) N/A 2001-03-01 RATIONALE: Giving caspofungin acetate may be effective in preventing or controlling fever and neutropenia caused by chemotherapy or bone marrow transplantation. PURPOSE: Clinical trial to study the effectiveness of caspofungin acetate in treating children who have fever and neutropenia caused by a weakened immune system.
NCT00082524 ↗ Documented Candida or Aspergillus Infections in Pediatric Patients (0991-043) Completed Merck Sharp & Dohme Corp. Phase 2 2004-04-01 This study is an open label, noncomparative study using an investigational agent for the treatment of documented Candida or Aspergillus infections in pediatric patients (ages 3 months-17 years).
NCT00082537 ↗ MK0991 Versus Amphotericin B for Empirical Therapy in Febrile, Neutropenic Pediatric Patients (0991-044) Completed Merck Sharp & Dohme Corp. Phase 2 2004-04-01 This study is a double-blind, randomized study of MK0991 versus liposomal amphotericin B in the empirical treatment of pediatric patients (ages 2 through 17 years) who have an absolute neutrophil count (ANC) below 500/microliter and who have fever despite broad antibiotic coverage. Such patients would be candidates for empirical therapy with an intravenous anti-fungal agent.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Caspofungin Acetate

Condition Name

Condition Name for Caspofungin Acetate
Intervention Trials
Fungal Infection 8
Candidiasis 4
Neutropenia 3
Aspergillosis 2
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Condition MeSH

Condition MeSH for Caspofungin Acetate
Intervention Trials
Mycoses 11
Candidiasis 7
Neutropenia 7
Infections 5
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Clinical Trial Locations for Caspofungin Acetate

Trials by Country

Trials by Country for Caspofungin Acetate
Location Trials
United States 77
Canada 10
Spain 5
Belgium 2
Germany 2
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Trials by US State

Trials by US State for Caspofungin Acetate
Location Trials
New York 3
Tennessee 3
District of Columbia 2
Indiana 2
Iowa 2
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Clinical Trial Progress for Caspofungin Acetate

Clinical Trial Phase

Clinical Trial Phase for Caspofungin Acetate
Clinical Trial Phase Trials
Phase 4 1
Phase 3 9
Phase 2 8
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Clinical Trial Status

Clinical Trial Status for Caspofungin Acetate
Clinical Trial Phase Trials
Completed 16
Terminated 2
Not yet recruiting 1
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Clinical Trial Sponsors for Caspofungin Acetate

Sponsor Name

Sponsor Name for Caspofungin Acetate
Sponsor Trials
Merck Sharp & Dohme Corp. 11
National Cancer Institute (NCI) 5
Children's Oncology Group 2
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Sponsor Type

Sponsor Type for Caspofungin Acetate
Sponsor Trials
Other 11
Industry 11
NIH 5
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