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Last Updated: July 3, 2022

CLINICAL TRIALS PROFILE FOR CANAGLIFLOZIN; METFORMIN HYDROCHLORIDE


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All Clinical Trials for Canagliflozin; Metformin Hydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00968812 ↗ CANagliflozin Treatment And Trial Analysis-Sulfonylurea (CANTATA-SU) SGLT2 Add-on to Metformin Versus Glimepiride Completed Janssen Research & Development, LLC Phase 3 2009-09-01 The purpose of this study is to demonstrate the efficacy, safety, and tolerability of canagliflozin (JNJ-28431754) compared with glimepiride in patients with type 2 diabetes mellitus with inadequate control despite treatment with metformin.
NCT01081834 ↗ The CANTATA-M (CANagliflozin Treatment and Trial Analysis - Monotherapy) Trial Completed Janssen Research & Development, LLC Phase 3 2010-03-01 The purpose of this study is to evaluate the efficacy, safety, and tolerability of 2 different doses of canagliflozin administered as monotherapy compared with placebo in patients with type 2 diabetes mellitus (T2DM) inadequately controlled with diet and exercise.
NCT01106625 ↗ The CANTATA-MSU Trial (CANagliflozin Treatment And Trial Analysis - Metformin and SUlphonylurea) Completed Janssen Research & Development, LLC Phase 3 2010-05-01 The purpose of this study is to evaluate the efficacy and safety of 2 different doses of canagliflozin compared with placebo in patients with type 2 diabetes mellitus who are receiving treatment with metformin and sulphonylurea and have inadequate glycemic (blood sugar) control.
NCT01106677 ↗ The CANTATA-D Trial (CANagliflozin Treatment and Trial Analysis - DPP-4 Inhibitor Comparator Trial) Completed Janssen Research & Development, LLC Phase 3 2010-05-01 The purpose of this study is to evaluate the efficacy and safety of canagliflozin compared with sitagliptin and placebo in patients with type 2 diabetes mellitus who are receiving treatment with metformin monotherapy (i.e., treatment with a single drug) and have inadequate glycemic (blood sugar) control.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Canagliflozin; Metformin Hydrochloride

Condition Name

Condition Name for Canagliflozin; Metformin Hydrochloride
Intervention Trials
Diabetes Mellitus, Type 2 18
Healthy 16
Healthy Volunteers 4
Type 2 Diabetes 2
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Condition MeSH

Condition MeSH for Canagliflozin; Metformin Hydrochloride
Intervention Trials
Diabetes Mellitus 26
Diabetes Mellitus, Type 2 25
Fatty Liver 3
Non-alcoholic Fatty Liver Disease 3
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Clinical Trial Locations for Canagliflozin; Metformin Hydrochloride

Trials by Country

Trials by Country for Canagliflozin; Metformin Hydrochloride
Location Trials
United States 250
Canada 25
India 15
Mexico 11
United Kingdom 6
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Trials by US State

Trials by US State for Canagliflozin; Metformin Hydrochloride
Location Trials
Arizona 17
Texas 13
Florida 13
California 13
Ohio 10
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Clinical Trial Progress for Canagliflozin; Metformin Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Canagliflozin; Metformin Hydrochloride
Clinical Trial Phase Trials
Phase 4 10
Phase 3 9
Phase 2 3
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Clinical Trial Status

Clinical Trial Status for Canagliflozin; Metformin Hydrochloride
Clinical Trial Phase Trials
Completed 42
Recruiting 4
Not yet recruiting 1
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Clinical Trial Sponsors for Canagliflozin; Metformin Hydrochloride

Sponsor Name

Sponsor Name for Canagliflozin; Metformin Hydrochloride
Sponsor Trials
Janssen Research & Development, LLC 31
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 5
University of Leicester 2
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Sponsor Type

Sponsor Type for Canagliflozin; Metformin Hydrochloride
Sponsor Trials
Industry 42
Other 17
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Serving leading biopharmaceutical companies globally:

Boehringer Ingelheim
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AstraZeneca
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Dow
Colorcon

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