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Last Updated: January 21, 2020

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CLINICAL TRIALS PROFILE FOR CABOZANTINIB S-MALATE

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All Clinical Trials for Cabozantinib S-malate

Trial ID Title Status Sponsor Phase Start Date Summary
NCT01708954 Erlotinib Hydrochloride and Cabozantinib-s-Malate Alone or in Combination as Second or Third Line Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer Active, not recruiting National Cancer Institute (NCI) Phase 2 2013-02-01 This randomized phase II trial studies how well giving erlotinib hydrochloride and cabozantinib-s-malate alone or in combination works as second or third line therapy in treating patient with stage IV non-small cell lung cancer. Erlotinib hydrochloride and cabozantinib-s-malate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It is not yet known whether giving erlotinib hydrochloride together with cabozantinib-s-malate is more effective than erlotinib hydrochloride or cabozantinib-s-malate alone in treating non-small cell lung cancer.
NCT01709435 Cabozantinib S-Malate in Treating Younger Patients With Recurrent or Refractory Solid Tumors Active, not recruiting National Cancer Institute (NCI) Phase 1 2012-11-01 This phase I trial studies the side effects and best dose of cabozantinib S-malate in treating younger patients with solid tumors that have come back or no longer respond to treatment. Cabozantinib S-malate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
NCT01716715 Cabozantinib or Paclitaxel in Treating Patients With Persistent or Recurrent Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer Active, not recruiting National Cancer Institute (NCI) Phase 2 2012-11-01 This randomized phase II trial studies how well giving cabozantinib-s-malate or paclitaxel works in treating patients with persistent or recurrent epithelial ovarian, fallopian tube, or primary peritoneal cavity cancer. Cabozantinib-s-malate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether cabozantinib-s-malate or paclitaxel is more effective at treating patients with persistent or recurrent epithelial ovarian, fallopian tube, or primary peritoneal cavity cancer.
NCT01811212 Cabozantinib-S-Malate in Treating Patients With Refractory Thyroid Cancer Suspended Exelixis Phase 2 2013-05-01 This phase II trial studies how well cabozantinib-s-malate works in treating patients with thyroid cancer that does not respond to treatment. Cabozantinib-s-malate may stop the growth of thyroid cancer by blocking some of the enzymes needed for cell growth. Cabozantinib-s-malate may also stop the growth of thyroid cancer by blocking blood flow to the tumor.
NCT01811212 Cabozantinib-S-Malate in Treating Patients With Refractory Thyroid Cancer Suspended National Cancer Institute (NCI) Phase 2 2013-05-01 This phase II trial studies how well cabozantinib-s-malate works in treating patients with thyroid cancer that does not respond to treatment. Cabozantinib-s-malate may stop the growth of thyroid cancer by blocking some of the enzymes needed for cell growth. Cabozantinib-s-malate may also stop the growth of thyroid cancer by blocking blood flow to the tumor.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Cabozantinib S-malate

Condition Name

Condition Name for Cabozantinib S-malate
Intervention Trials
Papillary Renal Cell Carcinoma 2
Recurrent Ewing Sarcoma 2
Solid Neoplasm 2
Stage III Renal Cell Cancer 2
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Condition MeSH

Condition MeSH for Cabozantinib S-malate
Intervention Trials
Carcinoma 13
Neoplasms 5
Carcinoma, Renal Cell 5
Thyroid Neoplasms 5
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Clinical Trial Locations for Cabozantinib S-malate

Trials by Country

Trials by Country for Cabozantinib S-malate
Location Trials
United States 301
Canada 9
France 1
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Trials by US State

Trials by US State for Cabozantinib S-malate
Location Trials
California 12
Michigan 11
Pennsylvania 11
Ohio 11
Illinois 10
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Clinical Trial Progress for Cabozantinib S-malate

Clinical Trial Phase

Clinical Trial Phase for Cabozantinib S-malate
Clinical Trial Phase Trials
Phase 2 15
Phase 1 4
N/A 1
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Clinical Trial Status

Clinical Trial Status for Cabozantinib S-malate
Clinical Trial Phase Trials
Active, not recruiting 8
Not yet recruiting 4
Recruiting 4
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Clinical Trial Sponsors for Cabozantinib S-malate

Sponsor Name

Sponsor Name for Cabozantinib S-malate
Sponsor Trials
National Cancer Institute (NCI) 19
Exelisis 1
Barbara Ann Karmanos Cancer Institute 1
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Sponsor Type

Sponsor Type for Cabozantinib S-malate
Sponsor Trials
NIH 19
Other 2
U.S. Fed 1
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