Last Updated: November 8, 2026

CLINICAL TRIALS PROFILE FOR CEVIMELINE HYDROCHLORIDE

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All Clinical Trials for CEVIMELINE HYDROCHLORIDE

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00017511 ↗	Cevimeline in Treating Patients With Dry Mouth Caused by Radiation Therapy for Head and Neck Cancer	Completed	Daiichi Sankyo Inc.	Phase 3	2001-06-01	RATIONALE: Cevimeline may be effective in treating dry mouth that is caused by radiation therapy for head and neck cancer. It is not yet known if cevimeline is more effective than no therapy in treating dry mouth caused by radiation therapy. PURPOSE: Randomized phase III trial to determine the effectiveness of cevimeline in treating patients who have dryness of the mouth caused by radiation therapy for head and neck cancer.
NCT00017511 ↗	Cevimeline in Treating Patients With Dry Mouth Caused by Radiation Therapy for Head and Neck Cancer	Completed	Daiichi Sankyo, Inc.	Phase 3	2001-06-01	RATIONALE: Cevimeline may be effective in treating dry mouth that is caused by radiation therapy for head and neck cancer. It is not yet known if cevimeline is more effective than no therapy in treating dry mouth caused by radiation therapy. PURPOSE: Randomized phase III trial to determine the effectiveness of cevimeline in treating patients who have dryness of the mouth caused by radiation therapy for head and neck cancer.
NCT00466388 ↗	Study of the Effectiveness of Cevimeline on Oral Health in Patients With Radiation Induced Xerostomia	Completed	Duke University	Phase 4	2007-05-01	The purpose of this study is to determine the effectiveness of cevimeline (versus placebo) on the oral health of patients who have dry mouth which was caused by radiation therapy that was given for treatment of head and/or neck cancer.
NCT00466388 ↗	Study of the Effectiveness of Cevimeline on Oral Health in Patients With Radiation Induced Xerostomia	Completed	American Academy of Otolaryngology-Head and Neck Surgery Foundation	Phase 4	2007-05-01	The purpose of this study is to determine the effectiveness of cevimeline (versus placebo) on the oral health of patients who have dry mouth which was caused by radiation therapy that was given for treatment of head and/or neck cancer.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for CEVIMELINE HYDROCHLORIDE

Condition Name

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Condition Name for CEVIMELINE HYDROCHLORIDE
Intervention	Trials
Dry Mouth	3
Xerostomia	2
Oral Complications	1
Overactive Bladder Syndrome	1
[disabled in preview]	1
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Condition MeSH

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Condition MeSH for CEVIMELINE HYDROCHLORIDE
Intervention	Trials
Xerostomia	5
Radiation Injuries	1
Head and Neck Neoplasms	1
Dry Eye Syndromes	1
[disabled in preview]	1
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Clinical Trial Locations for CEVIMELINE HYDROCHLORIDE

Trials by Country

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Trials by Country for CEVIMELINE HYDROCHLORIDE
Location	Trials
United States	43
Australia	2
Taiwan	2
Egypt	1
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Trials by US State

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Trials by US State for CEVIMELINE HYDROCHLORIDE
Location	Trials
Kentucky	3
Colorado	2
Nevada	2
Virginia	2
Pennsylvania	2
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Clinical Trial Progress for CEVIMELINE HYDROCHLORIDE

Clinical Trial Phase

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Clinical Trial Phase for CEVIMELINE HYDROCHLORIDE
Clinical Trial Phase	Trials
PHASE4	1
PHASE2	1
Phase 4	2
[disabled in preview]	1
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Clinical Trial Status

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Clinical Trial Status for CEVIMELINE HYDROCHLORIDE
Clinical Trial Phase	Trials
Completed	6
Recruiting	2
[disabled in preview]	0
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Clinical Trial Sponsors for CEVIMELINE HYDROCHLORIDE

Sponsor Name

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Sponsor Name for CEVIMELINE HYDROCHLORIDE
Sponsor	Trials
Roxane Laboratories	2
BioTheraVision, Inc.	1
Daiichi Sankyo Inc.	1
[disabled in preview]	1
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Sponsor Type

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Sponsor Type for CEVIMELINE HYDROCHLORIDE
Sponsor	Trials
Industry	5
Other	5
[disabled in preview]	0
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