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Last Updated: January 27, 2020

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CLINICAL TRIALS PROFILE FOR BUPROPION HYDROCHLORIDE; NALTREXONE HYDROCHLORIDE

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All Clinical Trials for Bupropion Hydrochloride; Naltrexone Hydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00129246 Low-Dose Naltrexone Combined With Bupropion to Stop Smoking With Less Weight Gain Completed National Institute on Alcohol Abuse and Alcoholism (NIAAA) Phase 1/Phase 2 2004-12-01 This study will test a combination of the drugs naltrexone and bupropion with weight-concerned smokers to investigate whether or not this combination of drugs improves smoking cessation quit rates and minimizes post quit weight gain.
NCT00129246 Low-Dose Naltrexone Combined With Bupropion to Stop Smoking With Less Weight Gain Completed Yale University Phase 1/Phase 2 2004-12-01 This study will test a combination of the drugs naltrexone and bupropion with weight-concerned smokers to investigate whether or not this combination of drugs improves smoking cessation quit rates and minimizes post quit weight gain.
NCT00208169 Abilify Therapy for Reducing Comorbid Substance Abuse Completed Bristol-Myers Squibb Phase 4 2005-03-01 It is hypothesized that the use of aripiprazole (Abilify) in patients with alcohol and/or drug dependence with comorbid psychiatric conditions will lead to: - Reduction in the amount of alcohol and/or drugs used as measured by the Time Line Follow Back (TLFB) and the Addiction Severity Index (ASI) - Reduction in cravings for alcohol and drugs as measured by the Penn Alcohol Craving Scale - Reduction in symptoms of co-morbid psychiatric disorders compared to before starting aripiprazole.
NCT00208169 Abilify Therapy for Reducing Comorbid Substance Abuse Completed Creighton University Phase 4 2005-03-01 It is hypothesized that the use of aripiprazole (Abilify) in patients with alcohol and/or drug dependence with comorbid psychiatric conditions will lead to: - Reduction in the amount of alcohol and/or drugs used as measured by the Time Line Follow Back (TLFB) and the Addiction Severity Index (ASI) - Reduction in cravings for alcohol and drugs as measured by the Penn Alcohol Craving Scale - Reduction in symptoms of co-morbid psychiatric disorders compared to before starting aripiprazole.
NCT00364871 Efficacy and Safety Study of Combination Therapy to Treat Uncomplicated Obesity Completed Orexigen Therapeutics, Inc Phase 2 2005-04-01 The purpose of this study is to determine the efficacy and safety of 3 combinations of naltrexone and bupropion SR compared to naltrexone alone, bupropion SR alone or placebo.
NCT00419731 Study of Bupropion Versus Bupropion + Naltrexone for Smoking Cessation Unknown status National Institute on Drug Abuse (NIDA) Phase 2/Phase 3 2006-11-01 The purpose of this study is to compare the effects of bupropion + placebo to bupropion + naltrexone as treatments to help smokers quit.
NCT00419731 Study of Bupropion Versus Bupropion + Naltrexone for Smoking Cessation Unknown status University of Minnesota - Clinical and Translational Science Institute Phase 2/Phase 3 2006-11-01 The purpose of this study is to compare the effects of bupropion + placebo to bupropion + naltrexone as treatments to help smokers quit.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Bupropion Hydrochloride; Naltrexone Hydrochloride

Condition Name

Condition Name for Bupropion Hydrochloride; Naltrexone Hydrochloride
Intervention Trials
Obesity 18
Overweight 8
Binge-Eating Disorder 5
Nicotine Dependence 3
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Condition MeSH

Condition MeSH for Bupropion Hydrochloride; Naltrexone Hydrochloride
Intervention Trials
Overweight 11
Disease 7
Obesity 7
Feeding and Eating Disorders 6
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Clinical Trial Locations for Bupropion Hydrochloride; Naltrexone Hydrochloride

Trials by Country

Trials by Country for Bupropion Hydrochloride; Naltrexone Hydrochloride
Location Trials
United States 204
Korea, Republic of 1
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Trials by US State

Trials by US State for Bupropion Hydrochloride; Naltrexone Hydrochloride
Location Trials
Connecticut 13
California 11
Texas 10
South Carolina 8
North Carolina 8
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Clinical Trial Progress for Bupropion Hydrochloride; Naltrexone Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Bupropion Hydrochloride; Naltrexone Hydrochloride
Clinical Trial Phase Trials
Phase 4 6
Phase 3 7
Phase 2/Phase 3 6
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Clinical Trial Status

Clinical Trial Status for Bupropion Hydrochloride; Naltrexone Hydrochloride
Clinical Trial Phase Trials
Completed 18
Recruiting 9
Terminated 2
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Clinical Trial Sponsors for Bupropion Hydrochloride; Naltrexone Hydrochloride

Sponsor Name

Sponsor Name for Bupropion Hydrochloride; Naltrexone Hydrochloride
Sponsor Trials
Orexigen Therapeutics, Inc 14
Yale University 9
National Institute on Drug Abuse (NIDA) 6
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Sponsor Type

Sponsor Type for Bupropion Hydrochloride; Naltrexone Hydrochloride
Sponsor Trials
Other 21
Industry 18
NIH 12
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