CLINICAL TRIALS PROFILE FOR BUPROPION HYDROCHLORIDE; NALTREXONE HYDROCHLORIDE
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All Clinical Trials for Bupropion Hydrochloride; Naltrexone Hydrochloride
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00129246 ↗ | Low-Dose Naltrexone Combined With Bupropion to Stop Smoking With Less Weight Gain | Completed | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 1/Phase 2 | 2004-12-01 | This study will test a combination of the drugs naltrexone and bupropion with weight-concerned smokers to investigate whether or not this combination of drugs improves smoking cessation quit rates and minimizes post quit weight gain. |
| NCT00129246 ↗ | Low-Dose Naltrexone Combined With Bupropion to Stop Smoking With Less Weight Gain | Completed | Yale University | Phase 1/Phase 2 | 2004-12-01 | This study will test a combination of the drugs naltrexone and bupropion with weight-concerned smokers to investigate whether or not this combination of drugs improves smoking cessation quit rates and minimizes post quit weight gain. |
| NCT00208169 ↗ | Abilify Therapy for Reducing Comorbid Substance Abuse | Completed | Bristol-Myers Squibb | Phase 4 | 2005-03-01 | It is hypothesized that the use of aripiprazole (Abilify) in patients with alcohol and/or drug dependence with comorbid psychiatric conditions will lead to: - Reduction in the amount of alcohol and/or drugs used as measured by the Time Line Follow Back (TLFB) and the Addiction Severity Index (ASI) - Reduction in cravings for alcohol and drugs as measured by the Penn Alcohol Craving Scale - Reduction in symptoms of co-morbid psychiatric disorders compared to before starting aripiprazole. |
| NCT00208169 ↗ | Abilify Therapy for Reducing Comorbid Substance Abuse | Completed | Creighton University | Phase 4 | 2005-03-01 | It is hypothesized that the use of aripiprazole (Abilify) in patients with alcohol and/or drug dependence with comorbid psychiatric conditions will lead to: - Reduction in the amount of alcohol and/or drugs used as measured by the Time Line Follow Back (TLFB) and the Addiction Severity Index (ASI) - Reduction in cravings for alcohol and drugs as measured by the Penn Alcohol Craving Scale - Reduction in symptoms of co-morbid psychiatric disorders compared to before starting aripiprazole. |
| NCT00364871 ↗ | Efficacy and Safety Study of Combination Therapy to Treat Uncomplicated Obesity | Completed | Orexigen Therapeutics, Inc | Phase 2 | 2005-04-01 | The purpose of this study is to determine the efficacy and safety of 3 combinations of naltrexone and bupropion SR compared to naltrexone alone, bupropion SR alone or placebo. |
| NCT00419731 ↗ | Study of Bupropion Versus Bupropion + Naltrexone for Smoking Cessation | Unknown status | National Institute on Drug Abuse (NIDA) | Phase 2/Phase 3 | 2006-11-01 | The purpose of this study is to compare the effects of bupropion + placebo to bupropion + naltrexone as treatments to help smokers quit. |
| NCT00419731 ↗ | Study of Bupropion Versus Bupropion + Naltrexone for Smoking Cessation | Unknown status | University of Minnesota | Phase 2/Phase 3 | 2006-11-01 | The purpose of this study is to compare the effects of bupropion + placebo to bupropion + naltrexone as treatments to help smokers quit. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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