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Last Updated: March 29, 2024

CLINICAL TRIALS PROFILE FOR BUMETANIDE


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All Clinical Trials for Bumetanide

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00372762 ↗ Bumetanide Versus Furosemide in Heart Failure Withdrawn University of Western Ontario, Canada Phase 3 2011-01-01 Patients with NYHA FC II-III heart failure will be randomized in a cross-over fashion to 8 weeks of bumetanide versus furosemide therapy (equipotent dose), to test whether bumetanide therapy has a superior effect on insulin resistance compared to furosemide. Patients will be subject to a frequently sampled intravenous glucose tolerance test (FSIGT) with minimal model (MINMOD) analysis to assess insulin resistance and to a 6-minute walk test (6MWT) to assess functional capacity; patient recruitment and retention success, as well as medication adherence, will also be assessed.
NCT00372762 ↗ Bumetanide Versus Furosemide in Heart Failure Withdrawn Lawson Health Research Institute Phase 3 2011-01-01 Patients with NYHA FC II-III heart failure will be randomized in a cross-over fashion to 8 weeks of bumetanide versus furosemide therapy (equipotent dose), to test whether bumetanide therapy has a superior effect on insulin resistance compared to furosemide. Patients will be subject to a frequently sampled intravenous glucose tolerance test (FSIGT) with minimal model (MINMOD) analysis to assess insulin resistance and to a 6-minute walk test (6MWT) to assess functional capacity; patient recruitment and retention success, as well as medication adherence, will also be assessed.
NCT00830531 ↗ Pilot Study of Bumetanide for Newborn Seizures Completed Charles H. Hood Foundation Phase 1 2010-01-01 The main goal of the study is to obtain pharmacokinetic and safety data of bumetanide in newborns with refractory seizures. The overall hypothesis is that bumetanide, added to conventional antiepileptic (antiseizure) medications, will be a safe and well tolerated medication, compared with conventional antiepileptic drugs alone.
NCT00830531 ↗ Pilot Study of Bumetanide for Newborn Seizures Completed Citizens United for Research in Epilepsy Phase 1 2010-01-01 The main goal of the study is to obtain pharmacokinetic and safety data of bumetanide in newborns with refractory seizures. The overall hypothesis is that bumetanide, added to conventional antiepileptic (antiseizure) medications, will be a safe and well tolerated medication, compared with conventional antiepileptic drugs alone.
NCT00830531 ↗ Pilot Study of Bumetanide for Newborn Seizures Completed Harvard Catalyst- Harvard Clinical and Translational Science Center Phase 1 2010-01-01 The main goal of the study is to obtain pharmacokinetic and safety data of bumetanide in newborns with refractory seizures. The overall hypothesis is that bumetanide, added to conventional antiepileptic (antiseizure) medications, will be a safe and well tolerated medication, compared with conventional antiepileptic drugs alone.
NCT00830531 ↗ Pilot Study of Bumetanide for Newborn Seizures Completed Mooney Family Initiative for Translational Studies in Rare Diseases, Boston Children's Hospital Phase 1 2010-01-01 The main goal of the study is to obtain pharmacokinetic and safety data of bumetanide in newborns with refractory seizures. The overall hypothesis is that bumetanide, added to conventional antiepileptic (antiseizure) medications, will be a safe and well tolerated medication, compared with conventional antiepileptic drugs alone.
NCT00830531 ↗ Pilot Study of Bumetanide for Newborn Seizures Completed National Institute of Neurological Disorders and Stroke (NINDS) Phase 1 2010-01-01 The main goal of the study is to obtain pharmacokinetic and safety data of bumetanide in newborns with refractory seizures. The overall hypothesis is that bumetanide, added to conventional antiepileptic (antiseizure) medications, will be a safe and well tolerated medication, compared with conventional antiepileptic drugs alone.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Bumetanide

Condition Name

Condition Name for Bumetanide
Intervention Trials
Heart Failure 5
Acute Decompensated Heart Failure 3
Autism Spectrum Disorder (ASD) 2
Congestive Heart Failure 2
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Condition MeSH

Condition MeSH for Bumetanide
Intervention Trials
Heart Failure 13
Autistic Disorder 5
Renal Insufficiency, Chronic 3
Child Development Disorders, Pervasive 3
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Clinical Trial Locations for Bumetanide

Trials by Country

Trials by Country for Bumetanide
Location Trials
France 20
United States 11
Italy 10
Spain 8
Poland 8
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Trials by US State

Trials by US State for Bumetanide
Location Trials
Texas 2
New York 2
Massachusetts 1
Illinois 1
New Jersey 1
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Clinical Trial Progress for Bumetanide

Clinical Trial Phase

Clinical Trial Phase for Bumetanide
Clinical Trial Phase Trials
Phase 4 5
Phase 3 6
Phase 2 6
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Clinical Trial Status

Clinical Trial Status for Bumetanide
Clinical Trial Phase Trials
Completed 9
Not yet recruiting 5
Unknown status 3
[disabled in preview] 11
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Clinical Trial Sponsors for Bumetanide

Sponsor Name

Sponsor Name for Bumetanide
Sponsor Trials
ADIR, a Servier Group company 2
Yale University 2
Institut de Recherches Internationales Servier 2
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Sponsor Type

Sponsor Type for Bumetanide
Sponsor Trials
Other 45
Industry 12
NIH 1
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