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Last Updated: March 29, 2024

CLINICAL TRIALS PROFILE FOR BUTORPHANOL TARTRATE


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All Clinical Trials for BUTORPHANOL TARTRATE

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00510666 ↗ Comparison of Butorphanol and Tramadol Associated Patient-Controlled Analgesia (PCA) After Hysterectomy Completed HRSA/Maternal and Child Health Bureau Phase 4 2007-01-01 Intravenous patient-controlled analgesia (PCA) is a popular technique for postoperative pain management. Although several drugs are recognized as effective therapeutic options, optimal selection of drugs in hysterectomy patients underwent different anesthesia treatments remains unknown explicitly. The investigators hypothesized that butorphanol and tramadol can produce different analgesic effects with intravenous PCA after abdominal hysterectomy.
NCT00510666 ↗ Comparison of Butorphanol and Tramadol Associated Patient-Controlled Analgesia (PCA) After Hysterectomy Completed Nanjing Medical University Phase 4 2007-01-01 Intravenous patient-controlled analgesia (PCA) is a popular technique for postoperative pain management. Although several drugs are recognized as effective therapeutic options, optimal selection of drugs in hysterectomy patients underwent different anesthesia treatments remains unknown explicitly. The investigators hypothesized that butorphanol and tramadol can produce different analgesic effects with intravenous PCA after abdominal hysterectomy.
NCT00738192 ↗ Comparison of Analgesic Efficacy of Fentanyl, Sufentanil and Butorphanol After Remifentanil Anesthesia Completed Nanjing Medical University Phase 4 2008-07-01 Fast awakening from anesthesia is one of the major characteristics of remifentanil-associated anesthetic induction and maintenance, whereas corresponding pain during awakening influences patient's rehabilitation strongly. In addition, such early postoperative pain results in significant stress responses, which displays as further release of stress hormones such as cortisol and β-endorphin as well. How to prevent such acute pain resulting from remifentanil's fast metabolism endows clinical significance. This study is designed to compare the analgesic efficacy of fentanyl, sufentanil and butorphanol delivered after gynecological laparoscopic surgeries that underwent remifentanil induction and maintenance, and investigate corresponding influence on the levels of blood cortisol and β-endorphin.
NCT00795314 ↗ Propofol-butorphanol Anesthesia During Uterine Curettage Completed Nanjing Medical University Phase 4 2008-11-01 Uterine curettage is usually performed under the anesthesia of propofol-fentanyl or para-cervical block,of which generally has significant incidence of respiratory depression which increases the demand on intraoperative monitoring, or has unavoidable insufficient blockade which results in intraoperative suffering of pain. Butorphanol is an analgesic with combined effects on mu and kappa opioid receptors leading to a role as analgesia and sedation. The investigators hypothesized that combined propofol with butorphanol during uterine curettage would produce optimal effectiveness of these two drugs by adding sedative and analgesic effects together. In addition, it would decrease the intraoperative consumption of propofol without increase the incidence of side effects. Furthermore, such combination would alleviate postoperative pain.
NCT02715154 ↗ Dexmedetomidine for Cesarean Section Completed The First Affiliated Hospital with Nanjing Medical University Phase 1 2015-06-01 Current cesarean section often chooses spinal anesthesia. And in order to avoid the impact of drugs on the fetus, before the delivery, anesthesiologist generally don't use sedative or analgesic drugs. However, the majority of puerperas would appear nervous, anxiety, fear and other psychological reactions in cesarean section. Although the placental transfer and the foetal metabolism of dexmedetomidine have been reported and the result show no adverse effects on neonates, but the placental transfer of dexmedetomidine in intravertebral anesthesia area was lack of systematical research. This study intends to use of dexmedetomidine in the cesarean section under epidural anesthesia and investigate its effects on the parturients' haemodynamics and the neonates' placental transfer and metabolism.
NCT03065530 ↗ Intravenous Dexmedetomidine for Cesarean Section Completed The First Affiliated Hospital with Nanjing Medical University Phase 4 2017-02-07 Nervous, anxiety, fear and other psychological reactions always appears in parturients during cesarean section. This study intends to investigate the effectiveness and safety of dexmedetomidine combined with butorphanol tartrate for postoperative analgesia and breastfeeding after caesarean section.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for BUTORPHANOL TARTRATE

Condition Name

Condition Name for BUTORPHANOL TARTRATE
Intervention Trials
Postoperative Pain 3
Analgesia 2
Abortion 1
Analgesia Obstetrical 1
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Condition MeSH

Condition MeSH for BUTORPHANOL TARTRATE
Intervention Trials
Pain, Postoperative 3
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Clinical Trial Locations for BUTORPHANOL TARTRATE

Trials by Country

Trials by Country for BUTORPHANOL TARTRATE
Location Trials
China 6
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Clinical Trial Progress for BUTORPHANOL TARTRATE

Clinical Trial Phase

Clinical Trial Phase for BUTORPHANOL TARTRATE
Clinical Trial Phase Trials
Phase 4 5
Phase 1 1
N/A 1
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Clinical Trial Status

Clinical Trial Status for BUTORPHANOL TARTRATE
Clinical Trial Phase Trials
Completed 5
Recruiting 1
Not yet recruiting 1
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Clinical Trial Sponsors for BUTORPHANOL TARTRATE

Sponsor Name

Sponsor Name for BUTORPHANOL TARTRATE
Sponsor Trials
Nanjing Medical University 3
The First Affiliated Hospital with Nanjing Medical University 2
HRSA/Maternal and Child Health Bureau 1
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Sponsor Type

Sponsor Type for BUTORPHANOL TARTRATE
Sponsor Trials
Other 6
U.S. Fed 1
Industry 1
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