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Last Updated: March 29, 2024

CLINICAL TRIALS PROFILE FOR BREVIBLOC IN PLASTIC CONTAINER


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All Clinical Trials for BREVIBLOC IN PLASTIC CONTAINER

Trial ID Title Status Sponsor Phase Start Date Summary
NCT01114971 ↗ Labetalol and Esmolol: Vital Signs and Post Operative Pain Management Completed Cedars-Sinai Medical Center Phase 4 2009-09-03 This study proposes to investigate the effects of labetalol or esmolol on managing the vital signs (like blood pressure and heart rate) during surgery, on pain management, and on the later recovery after surgery. It will also assess the cost-effectiveness of Labetalol and esmolol for outpatient surgery.
NCT01179113 ↗ Esmolol Infusion During Laminectomy: Effect on Quality of Recovery Terminated Cedars-Sinai Medical Center Phase 4 2011-06-01 The purpose of this study is to evaluate the effects of esmolol, a drug which is commonly administered during surgery to help control blood pressure and heart rate, on postoperative pain levels and requirements for pain medication.
NCT01208402 ↗ Esmolol for Treatment of Perioperative Tachycardia Terminated Baxter Healthcare Corporation Phase 3 2010-09-01 The purpose of this study is to find out if Esmolol is a safe and effective alternative treatment compared to standard treatment using a long acting beta blocker drug, in controlling abnormal heart rate before, during and immediately after surgery.
NCT01208402 ↗ Esmolol for Treatment of Perioperative Tachycardia Terminated Duke University Phase 3 2010-09-01 The purpose of this study is to find out if Esmolol is a safe and effective alternative treatment compared to standard treatment using a long acting beta blocker drug, in controlling abnormal heart rate before, during and immediately after surgery.
NCT01232400 ↗ Study to Evaluate Esmolol (Brevibloc) to Manage Cardiac Function in Patients With Subarachnoid Hemorrhage Withdrawn University of Michigan N/A 2014-07-01 The purpose of this study is to evaluate the clinical effect of esmolol treatment on cardiac function and electrophysiology; to assess the effects of esmolol treatment on serum adrenergic and cardiac biomarkers; to explore the safety of esmolol treatment shortly after subarachnoid hemorrhage (SAH). Patients will be followed for a maximum of 1 month after the index SAH. The primary outcome will be change in systolic function - ejection fraction by Simpson's rule (baseline versus Day 7 +/- 2 after SAH).
NCT01343329 ↗ Controlling Hyperadrenergic Activity in Neurologic Injury Withdrawn Johns Hopkins University Phase 1/Phase 2 2011-07-01 Traumatic brain injury (TBI) is frequently associated with a hyperadrenergic state accompanied by elevated levels of plasma catecholamines. In its more severe presentation, the hyperadrenergic state presents as dysautonomia, which is characterized by paroxysmal alteration in vital signs, including tachycardia. The investigators hypothesize that intravenous (IV) esmolol is as effective at controlling heart rate in hyperadrenergic states as oral propranolol, which is the standard of care. Our primary endpoint is efficacy of IV esmolol vs a PRN regimen of intermittent B-blockade in controlling heart rate below a pre-specified level (< 100 bpm) after Traumatic Brain Injury (TBI) or hemorrhagic neurologic injury. Heart rates will be recorded continuously as well as hourly.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for BREVIBLOC IN PLASTIC CONTAINER

Condition Name

Condition Name for BREVIBLOC IN PLASTIC CONTAINER
Intervention Trials
Septic Shock 3
Myocardial Ischemia 1
Drug Overdose 1
Myocardial Reperfusion Injury 1
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Condition MeSH

Condition MeSH for BREVIBLOC IN PLASTIC CONTAINER
Intervention Trials
Shock, Septic 3
Shock 3
Tachycardia 2
Autonomic Nervous System Diseases 1
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Clinical Trial Locations for BREVIBLOC IN PLASTIC CONTAINER

Trials by Country

Trials by Country for BREVIBLOC IN PLASTIC CONTAINER
Location Trials
United States 8
Brazil 6
Turkey 3
China 1
Egypt 1
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Trials by US State

Trials by US State for BREVIBLOC IN PLASTIC CONTAINER
Location Trials
Utah 2
California 2
Maryland 1
Michigan 1
Ohio 1
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Clinical Trial Progress for BREVIBLOC IN PLASTIC CONTAINER

Clinical Trial Phase

Clinical Trial Phase for BREVIBLOC IN PLASTIC CONTAINER
Clinical Trial Phase Trials
Phase 4 7
Phase 3 1
Phase 2 4
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Clinical Trial Status

Clinical Trial Status for BREVIBLOC IN PLASTIC CONTAINER
Clinical Trial Phase Trials
Completed 7
Unknown status 3
Withdrawn 3
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Clinical Trial Sponsors for BREVIBLOC IN PLASTIC CONTAINER

Sponsor Name

Sponsor Name for BREVIBLOC IN PLASTIC CONTAINER
Sponsor Trials
Cedars-Sinai Medical Center 2
Baxter Healthcare Corporation 2
Beth Israel Deaconess Medical Center 2
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Sponsor Type

Sponsor Type for BREVIBLOC IN PLASTIC CONTAINER
Sponsor Trials
Other 19
Industry 4
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