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Generated: December 11, 2018

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CLINICAL TRIALS PROFILE FOR AMOXICILLIN

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Clinical Trials for Amoxicillin

Trial ID Title Status Sponsor Phase Summary
NCT00001658 Amoxicillin for the Treatment of Pediatric Autoimmune Disorders Associated With Streptococcal Infections Completed National Institute of Mental Health (NIMH) Phase 4 Bacteria carry substances on their surface called antigens. When antigens come into contact with the right kinds of cells in the body an immune reaction is caused. This reaction is often the symptoms of sickness that a patient feels. In order for the body to fight off the attack of antigens, it creates substances called antibodies. Antibodies counter the action of antigens and make the bacteria harmless. However, the immune system must learn how to make the right antibodies for the right antigens. Sometimes the body creates antibodies that confuse normal tissues as foreign and attack them. This is called an autoimmune reaction and sometimes occurs when the body is exposed to certain bacteria. One bacteria known for causing autoimmune reactions is Group A beta-hemolytic Streptococcus (GABHS). This bacteria often causes throat infections commonly known as "strep throat". Some researchers believe that the autoimmune reaction associated with strep throat infections may cause neuropsychiatric disorders, like obsessive-compulsive disorder and/or tic disorder in children. As a result, each time a child with one of these disorders experiences an infection with GABHS his/her symptoms can reoccur or worsen. Researchers believe that by giving patients a certain antibiotic, they can prevent GABHS infection and thus prevent the return of symptoms. This study is designed to test the effectiveness of the antibiotic Amoxicillin for the treatment of Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections (PANDAS). Patients will receive Amoxicillin for six weeks and placebos "inactive sugar pills" for six weeks in order to see if the medication is truly working. Effectiveness of the treatment will be based on the presence or absence of symptoms. If at the end of the study Amoxicillin is proven to be effective treatment for PANDAS patients may be offered the opportunity to continue taking the medication for an additional six months.
NCT00002052 Prospective Comparison of Ampicillin / Amoxicillin Versus Ceftriaxone for the Treatment of Salmonella Infections in AIDS Patients Completed University of Southern California N/A To compare the effectiveness of standard treatment with parenteral ampicillin and oral amoxicillin compared to initial daily therapy with ceftriaxone followed by 3 times weekly suppressive treatment for salmonella infections in AIDS patients.
NCT00002149 Acupuncture and Herbal Treatment of Chronic HIV Sinusitis Completed Immune Enhancement Project N/A To compare Traditional Chinese Medicine versus standard antibiotic therapy consisting of pseudoephedrine ( Sudafed ) plus amoxicillin / clavulanate potassium combination ( Augmentin ) in reducing symptoms and recurrence of acute HIV-related sinusitis. Chronic sinusitis in HIV-infected individuals is a recurrent and persistent infection with potentially serious complications: it can exacerbate pulmonary disease, cause recurrences of life-threatening sepsis, and progress to central nervous system involvement. Symptoms of sinusitis in HIV patients are often refractory to aggressive Western medical management, and antibiotic intolerance can occur. Traditional Chinese Medicine consisting of acupuncture and herbal treatment may provide a low-risk, low-cost alternative to conventional antibiotic therapy.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Amoxicillin

Condition Name

Condition Name for Amoxicillin
Intervention Trials
Helicobacter Pylori Infection 58
Pneumonia 19
Healthy 17
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Condition MeSH

Condition MeSH for Amoxicillin
Intervention Trials
Helicobacter Infections 86
Infection 74
Communicable Diseases 54
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Clinical Trial Locations for Amoxicillin

Trials by Country

Trials by Country for Amoxicillin
Location Trials
United States 206
Canada 39
France 36
Taiwan 34
Germany 34
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Trials by US State

Trials by US State for Amoxicillin
Location Trials
California 16
Ohio 14
Texas 14
Pennsylvania 12
Florida 10
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Clinical Trial Progress for Amoxicillin

Clinical Trial Phase

Clinical Trial Phase for Amoxicillin
Clinical Trial Phase Trials
Phase 4 151
Phase 3 72
Phase 2/Phase 3 11
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Clinical Trial Status

Clinical Trial Status for Amoxicillin
Clinical Trial Phase Trials
Completed 193
Recruiting 81
Not yet recruiting 31
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Clinical Trial Sponsors for Amoxicillin

Sponsor Name

Sponsor Name for Amoxicillin
Sponsor Trials
National Taiwan University Hospital 18
Shanghai Jiao Tong University School of Medicine 11
GlaxoSmithKline 10
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Sponsor Type

Sponsor Type for Amoxicillin
Sponsor Trials
Other 451
Industry 109
NIH 11
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Serving hundreds of leading biopharmaceutical companies globally:

Colorcon
Moodys
Harvard Business School
Chinese Patent Office
Merck
Johnson and Johnson
UBS
Baxter
Cantor Fitzgerald

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