CLINICAL TRIALS PROFILE FOR AMILORIDE HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE
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All Clinical Trials for Amiloride Hydrochloride And Hydrochlorothiazide
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00007592 ↗ | Hypertension Screening and Treatment Program | Completed | US Department of Veterans Affairs | 1989-06-01 | Hypertension is one of the most common medical problems in the United States and in the VA health care system. It has been well-documented that hypertension can be effectively treated. However, there remain important unresolved clinical questions in the area of antihypertensive treatment. For example, how much is mortality affected by visit compliance, blood pressure control and type of antihypertensive agent? Or, are some regimens associated with more morbidity than others? Or, are there inexpensive regimens that are as effective as more expensive regimens? The amount of data that is available from this demonstration project (currently 6,100 patients) will help address these questions. The answers to these questions should result in better care for veterans with hypertension. | |
| NCT00007592 ↗ | Hypertension Screening and Treatment Program | Completed | VA Office of Research and Development | 1989-06-01 | Hypertension is one of the most common medical problems in the United States and in the VA health care system. It has been well-documented that hypertension can be effectively treated. However, there remain important unresolved clinical questions in the area of antihypertensive treatment. For example, how much is mortality affected by visit compliance, blood pressure control and type of antihypertensive agent? Or, are some regimens associated with more morbidity than others? Or, are there inexpensive regimens that are as effective as more expensive regimens? The amount of data that is available from this demonstration project (currently 6,100 patients) will help address these questions. The answers to these questions should result in better care for veterans with hypertension. | |
| NCT00224549 ↗ | PHARES Study: Management of Resistant Hypertension | Completed | Assistance Publique - Hôpitaux de Paris | Phase 4 | 2005-04-01 | The purpose of this study is to assess the efficacy of two different treatment regimens for treating resistant hypertension previously uncontrolled with at least 3 antihypertensive treatments. The study hypothesis is that these two regimens (one based on increasing diuretics and the other based on increasing renin angiotensin system blockage) may not differ in terms of efficacy. |
| NCT00394394 ↗ | Antihypertensive Effectiveness of the Associations of Hydrochlorothiazide and Amiloride and Hydrochlorothiazide and Enalapril | Completed | Hospital de Clinicas de Porto Alegre | Phase 2 | 2005-02-01 | The majority of hypertensive patients require antihypertensive associations to control their blood pressure. Most of clinical trials don't compare different associations using Hydrochlorothiazide 25 mg as the standard initial therapy and compare the associations using doses that are not equivalent. This randomized trial where patients and investigators are blinded and compares the effectiveness two associations: Hydrochlorothiazide and Amiloride and Hydrochlorothiazide and Enalapril. |
| NCT00638482 ↗ | Dose-Dependent Effect of Thiazide in Dent's Disease Hypercalciuria | Terminated | Assistance Publique - Hôpitaux de Paris | Phase 2/Phase 3 | 2003-07-01 | Intrarenal calcifications (nephrocalcinosis) is present in Dent's disease and likely contribute to progression toward renal failure. In order to prevent this complication it is usually proposed to treat affected patients during childhood with high doses of thiazides. |
| NCT01804777 ↗ | Epithelial Sodium Channel (ENaC) as a Novel Mechanism for Hypertension and Volume Expansion in Type 2 Diabetes | Terminated | Dialysis Clinic, Inc. | Early Phase 1 | 2013-03-01 | The purpose of this study is to determine with the administration of amiloride, observe an enhanced natriuresis, reduction in blood pressure and weight compared to the administration of hydrochlorothiazide in Type 2 Diabetics. |
| NCT01804777 ↗ | Epithelial Sodium Channel (ENaC) as a Novel Mechanism for Hypertension and Volume Expansion in Type 2 Diabetes | Terminated | University of Pittsburgh | Early Phase 1 | 2013-03-01 | The purpose of this study is to determine with the administration of amiloride, observe an enhanced natriuresis, reduction in blood pressure and weight compared to the administration of hydrochlorothiazide in Type 2 Diabetics. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
Clinical Trial Conditions for Amiloride Hydrochloride And Hydrochlorothiazide
Condition Name
| Condition Name for Amiloride Hydrochloride And Hydrochlorothiazide | |
| Intervention | Trials |
| Hypertension | 6 |
| Autosomal Dominant Hypocalcemia OR Primary Hypoparathyroidism Related to Other Cause But Complicated by Hypercalciuria Under Treatment | 1 |
| Chronic Kidney Disease | 1 |
| Chronic Kidney Diseases | 1 |
| [disabled in preview] | 0 |
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Clinical Trial Locations for Amiloride Hydrochloride And Hydrochlorothiazide
Trials by Country
Clinical Trial Progress for Amiloride Hydrochloride And Hydrochlorothiazide
Clinical Trial Phase
Clinical Trial Sponsors for Amiloride Hydrochloride And Hydrochlorothiazide
Sponsor Name
| Sponsor Name for Amiloride Hydrochloride And Hydrochlorothiazide | |
| Sponsor | Trials |
| Assistance Publique - Hôpitaux de Paris | 3 |
| Hospital de Clinicas de Porto Alegre | 2 |
| Guangdong Provincial People's Hospital | 1 |
| [disabled in preview] | 4 |
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