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Generated: February 23, 2019

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CLINICAL TRIALS PROFILE FOR AMILORIDE HYDROCHLORIDE; HYDROCHLOROTHIAZIDE

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Clinical Trials for Amiloride Hydrochloride; Hydrochlorothiazide

Trial ID Title Status Sponsor Phase Summary
NCT00007592 Hypertension Screening and Treatment Program Completed VA Office of Research and Development N/A Hypertension is one of the most common medical problems in the United States and in the VA health care system. It has been well-documented that hypertension can be effectively treated. However, there remain important unresolved clinical questions in the area of antihypertensive treatment. For example, how much is mortality affected by visit compliance, blood pressure control and type of antihypertensive agent? Or, are some regimens associated with more morbidity than others? Or, are there inexpensive regimens that are as effective as more expensive regimens? The amount of data that is available from this demonstration project (currently 6,100 patients) will help address these questions. The answers to these questions should result in better care for veterans with hypertension.
NCT00224549 PHARES Study: Management of Resistant Hypertension Completed Assistance Publique - Hôpitaux de Paris Phase 4 The purpose of this study is to assess the efficacy of two different treatment regimens for treating resistant hypertension previously uncontrolled with at least 3 antihypertensive treatments. The study hypothesis is that these two regimens (one based on increasing diuretics and the other based on increasing renin angiotensin system blockage) may not differ in terms of efficacy.
NCT00394394 Antihypertensive Effectiveness of the Associations of Hydrochlorothiazide and Amiloride and Hydrochlorothiazide and Enalapril Completed Hospital de Clinicas de Porto Alegre Phase 2 The majority of hypertensive patients require antihypertensive associations to control their blood pressure. Most of clinical trials don’t compare different associations using Hydrochlorothiazide 25 mg as the standard initial therapy and compare the associations using doses that are not equivalent. This randomized trial where patients and investigators are blinded and compares the effectiveness two associations: Hydrochlorothiazide and Amiloride and Hydrochlorothiazide and Enalapril.
NCT00638482 Dose-Dependent Effect of Thiazide in Dent's Disease Hypercalciuria Terminated Assistance Publique - Hôpitaux de Paris Phase 2/Phase 3 Intrarenal calcifications (nephrocalcinosis) is present in Dent's disease and likely contribute to progression toward renal failure. In order to prevent this complication it is usually proposed to treat affected patients during childhood with high doses of thiazides.
NCT01804777 Epithelial Sodium Channel (ENaC) as a Novel Mechanism for Hypertension and Volume Expansion in Type 2 Diabetes Terminated Dialysis Clinic, Inc. Phase 0 The purpose of this study is to determine with the administration of amiloride, observe an enhanced natriuresis, reduction in blood pressure and weight compared to the administration of hydrochlorothiazide in Type 2 Diabetics.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Amiloride Hydrochloride; Hydrochlorothiazide

Condition Name

Condition Name for Amiloride Hydrochloride; Hydrochlorothiazide
Intervention Trials
Hypertension 5
Proteinuria 1
Chronic Kidney Disease 1
Patients With Fungic Infections 1
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Condition MeSH

Condition MeSH for Amiloride Hydrochloride; Hydrochlorothiazide
Intervention Trials
Hypertension 3
Renal Insufficiency, Chronic 2
Kidney Diseases 2
Optic Neuritis 1
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Clinical Trial Locations for Amiloride Hydrochloride; Hydrochlorothiazide

Trials by Country

Trials by Country for Amiloride Hydrochloride; Hydrochlorothiazide
Location Trials
United States 11
France 4
Mexico 1
South Africa 1
Puerto Rico 1
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Trials by US State

Trials by US State for Amiloride Hydrochloride; Hydrochlorothiazide
Location Trials
Virginia 1
Tennessee 1
Pennsylvania 1
Ohio 1
Mississippi 1
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Clinical Trial Progress for Amiloride Hydrochloride; Hydrochlorothiazide

Clinical Trial Phase

Clinical Trial Phase for Amiloride Hydrochloride; Hydrochlorothiazide
Clinical Trial Phase Trials
Phase 4 4
Phase 2/Phase 3 1
Phase 2 3
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Clinical Trial Status

Clinical Trial Status for Amiloride Hydrochloride; Hydrochlorothiazide
Clinical Trial Phase Trials
Completed 4
Terminated 3
Recruiting 3
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Clinical Trial Sponsors for Amiloride Hydrochloride; Hydrochlorothiazide

Sponsor Name

Sponsor Name for Amiloride Hydrochloride; Hydrochlorothiazide
Sponsor Trials
Assistance Publique - Hôpitaux de Paris 3
Erasmus Medical Center 1
Hospital de Clinicas de Porto Alegre 1
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Sponsor Type

Sponsor Type for Amiloride Hydrochloride; Hydrochlorothiazide
Sponsor Trials
Other 11
Industry 2
U.S. Fed 1
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Serving hundreds of leading biopharmaceutical companies globally:

Mallinckrodt
UBS
Citi
Express Scripts
Covington
Chinese Patent Office
Chubb
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