Phase 2 Study of Lovastatin as Breast Cancer Chemoprevention
Terminated
Stanford University
Phase 2
2005-11-01
The study evaluates if a 6-month course of oral lovastatin at 80 mg/day would decrease
abnormal breast duct cytology in women with a high inherited breast cancer risk.
Lovastatin for the Treatment of Mildly Active Rheumatoid Arthritis
Terminated
Autoimmunity Centers of Excellence
Phase 2
2007-11-06
Rheumatoid arthritis (RA) is the most common inflammatory arthritis and a major health
problem. The purpose of this study is to determine the safety and effectiveness of lovastatin
for controlling inflammation in mildly active RA.
Lovastatin for the Treatment of Mildly Active Rheumatoid Arthritis
Terminated
National Institute of Allergy and Infectious Diseases (NIAID)
Phase 2
2007-11-06
Rheumatoid arthritis (RA) is the most common inflammatory arthritis and a major health
problem. The purpose of this study is to determine the safety and effectiveness of lovastatin
for controlling inflammation in mildly active RA.
Dose Escalation Phase I/II Study of Lovastatin With High-Dose Cytarabine for Refractory or Relapsed AML
Terminated
University of Iowa
Phase 1/Phase 2
2001-06-01
The purpose of this study is to test the safety and effectiveness of combining a drug known
as Lovastatin to the chemotherapy drug cytarabine. Lovastatin is currently used to lower
blood cholesterol levels and lab data suggests that it increases the anti-leukemia activity
of cytarabine. This research is being done because high doses of cytarabine induce remissions
in only about 25% of patients with acute myeloid leukemia.
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