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Last Updated: January 27, 2023

CLINICAL TRIALS PROFILE FOR ALTOPREV


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All Clinical Trials for Altoprev

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00285857 ↗ Phase 2 Study of Lovastatin as Breast Cancer Chemoprevention Terminated Stanford University Phase 2 2005-11-01 The study evaluates if a 6-month course of oral lovastatin at 80 mg/day would decrease abnormal breast duct cytology in women with a high inherited breast cancer risk.
NCT00302952 ↗ Lovastatin for the Treatment of Mildly Active Rheumatoid Arthritis Terminated Autoimmunity Centers of Excellence Phase 2 2007-11-06 Rheumatoid arthritis (RA) is the most common inflammatory arthritis and a major health problem. The purpose of this study is to determine the safety and effectiveness of lovastatin for controlling inflammation in mildly active RA.
NCT00302952 ↗ Lovastatin for the Treatment of Mildly Active Rheumatoid Arthritis Terminated National Institute of Allergy and Infectious Diseases (NIAID) Phase 2 2007-11-06 Rheumatoid arthritis (RA) is the most common inflammatory arthritis and a major health problem. The purpose of this study is to determine the safety and effectiveness of lovastatin for controlling inflammation in mildly active RA.
NCT00580970 ↗ Study of Effectiveness of Lovastatin to Prevent Radiation-Induced Rectal Injury Completed Hunter Holmes Mcguire Veteran Affairs Medical Center Phase 2 2007-04-01 Lovastatin may protect against late effects of radiation therapy in patients with prostate cancer
NCT00580970 ↗ Study of Effectiveness of Lovastatin to Prevent Radiation-Induced Rectal Injury Completed Virginia Commonwealth University Phase 2 2007-04-01 Lovastatin may protect against late effects of radiation therapy in patients with prostate cancer
NCT00583102 ↗ Dose Escalation Phase I/II Study of Lovastatin With High-Dose Cytarabine for Refractory or Relapsed AML Terminated University of Iowa Phase 1/Phase 2 2001-06-01 The purpose of this study is to test the safety and effectiveness of combining a drug known as Lovastatin to the chemotherapy drug cytarabine. Lovastatin is currently used to lower blood cholesterol levels and lab data suggests that it increases the anti-leukemia activity of cytarabine. This research is being done because high doses of cytarabine induce remissions in only about 25% of patients with acute myeloid leukemia.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Altoprev

Condition Name

Condition Name for Altoprev
Intervention Trials
Ovarian Cancer 1
Prostate Cancer 1
Rheumatoid Arthritis 1
Acute Myeloid Leukemia 1
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Condition MeSH

Condition MeSH for Altoprev
Intervention Trials
Leukemia, Myeloid 1
Leukemia 1
Hyperlipoproteinemias 1
Prostatic Neoplasms 1
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Clinical Trial Locations for Altoprev

Trials by Country

Trials by Country for Altoprev
Location Trials
United States 17
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Trials by US State

Trials by US State for Altoprev
Location Trials
Iowa 2
California 2
Massachusetts 1
Virginia 1
Utah 1
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Clinical Trial Progress for Altoprev

Clinical Trial Phase

Clinical Trial Phase for Altoprev
Clinical Trial Phase Trials
Phase 4 1
Phase 2 4
Phase 1/Phase 2 1
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Clinical Trial Status

Clinical Trial Status for Altoprev
Clinical Trial Phase Trials
Terminated 4
Completed 1
Recruiting 1
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Clinical Trial Sponsors for Altoprev

Sponsor Name

Sponsor Name for Altoprev
Sponsor Trials
University of Iowa 2
Autoimmunity Centers of Excellence 1
National Institute of Allergy and Infectious Diseases (NIAID) 1
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Sponsor Type

Sponsor Type for Altoprev
Sponsor Trials
Other 6
NIH 1
U.S. Fed 1
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Serving leading biopharmaceutical companies globally:

Medtronic
McKesson
Merck
Johnson and Johnson
McKinsey
Baxter

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