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CLINICAL TRIALS PROFILE FOR ALLOPURINOL

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Clinical Trials for Allopurinol

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00004314	Phase II Pilot Study of Aminoimidazole Carboxamide Riboside (AICAR), a Precursor of Purine Synthesis, for Lesch-Nyhan Disease	Completed	University of California, San Diego	Phase 2	OBJECTIVES: I. Determine the effects of aminoimidazole carboxamide riboside (AICAR) on hematologic manifestations of Lesch-Nyhan disease. II. Assess the behavioral and neurological benefits of AICAR in patients with Lesch-Nyhan disease. III. Examine the effect of AICAR on purine production.
NCT00004314	Phase II Pilot Study of Aminoimidazole Carboxamide Riboside (AICAR), a Precursor of Purine Synthesis, for Lesch-Nyhan Disease	Completed	National Center for Research Resources (NCRR)	Phase 2	OBJECTIVES: I. Determine the effects of aminoimidazole carboxamide riboside (AICAR) on hematologic manifestations of Lesch-Nyhan disease. II. Assess the behavioral and neurological benefits of AICAR in patients with Lesch-Nyhan disease. III. Examine the effect of AICAR on purine production.
NCT00004755	Allopurinol, Glucantime, or Allopurinol/Glucantime for Cutaneous Leishmaniasis in Brazil	Completed	Harvard School of Public Health	Phase 2	OBJECTIVE: Compare the efficacy and side effects of allopurinol versus glucantime versus allopurinol/glucantime in patients in Brazil with cutaneous leishmaniasis.

Clinical Trial Conditions for Allopurinol

Condition Name

Condition Name for Allopurinol
Intervention	Trials
Gout	35
Leukemia	16
Hyperuricemia	13

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Condition MeSH

Condition MeSH for Allopurinol
Intervention	Trials
Leukemia	29
Leukemia, Lymphoid	26
Gout	26

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Clinical Trial Locations for Allopurinol

Trials by Country

Trials by Country for Allopurinol
Location	Trials
United States	616
Canada	45
Australia	22
Spain	16
Poland	15

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Trials by US State

Trials by US State for Allopurinol
Location	Trials
Texas	53
California	28
Florida	22
North Carolina	20
New York	20

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Clinical Trial Progress for Allopurinol

Clinical Trial Phase

Clinical Trial Phase for Allopurinol
Clinical Trial Phase	Trials
Phase 4	37
Phase 3	34
Phase 2/Phase 3	5

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Clinical Trial Status

Clinical Trial Status for Allopurinol
Clinical Trial Phase	Trials
Completed	83
Recruiting	23
Active, not recruiting	20

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Clinical Trial Sponsors for Allopurinol

Sponsor Name

Sponsor Name for Allopurinol
Sponsor	Trials
M.D. Anderson Cancer Center	21
Ardea Biosciences, Inc.	14
Takeda	7

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Sponsor Type

Sponsor Type for Allopurinol
Sponsor	Trials
Other	193
Industry	71
NIH	21

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