Imiquimod Cream in Treating Patients With Basal Cell Skin Cancer
Completed
National Naval Medical Center
Phase 1
2004-01-01
RATIONALE: Biological therapies, such as imiquimod cream, work in different ways to stimulate
the immune system and stop tumor cells from growing.
PURPOSE: This randomized phase I trial is studying how well imiquimod cream works in treating
patients with basal cell skin cancer.
NY-ESO-1 Protein Vaccine With Imiquimod in Melanoma (Adjuvant Setting)
Completed
American Society of Clinical Oncology
Phase 1
2005-08-24
This was a Phase 1, single-arm, open-label, pilot study of NY-ESO-1 protein vaccination with
imiquimod as an adjuvant in patients with resected Stage IIB, IIC, and III malignant
melanoma. The primary study objective was to determine the safety of NY-ESO-1
protein/imiquimod treatment, and the secondary objective was to evaluate the immunogenicity
of treatment.
NY-ESO-1 Protein Vaccine With Imiquimod in Melanoma (Adjuvant Setting)
Completed
Cancer Research Institute (CRI)
Phase 1
2005-08-24
This was a Phase 1, single-arm, open-label, pilot study of NY-ESO-1 protein vaccination with
imiquimod as an adjuvant in patients with resected Stage IIB, IIC, and III malignant
melanoma. The primary study objective was to determine the safety of NY-ESO-1
protein/imiquimod treatment, and the secondary objective was to evaluate the immunogenicity
of treatment.
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