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Last Updated: April 16, 2024

CLINICAL TRIALS PROFILE FOR ACUVAIL


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All Clinical Trials for Acuvail

Trial ID Title Status Sponsor Phase Start Date Summary
NCT01001806 ↗ A Comparison of Peak Aqueous Penetration of Acuvail (Ketorolac 0.45%), Xibrom (Bromfenac 0.09%), and Nevanac (Nepafenac 0.1%)in Patients Undergoing Phacoemulsification Completed Allergan Phase 4 2009-10-01 Approximately 126 subjects scheduled to undergo cataract surgery by phacoemulsification, will be randomized in an even allocation (1:1:1) to either Acuvail, Xibrom, or Nevanac. Subjects will be instructed to begin dosing the study medication in the operative eye the day before surgery and continue dosing on the day of surgery. Beginning one hour before surgery, 1 drop of study medication will be instilled by operating room staff approximately every 15 minutes for a total of 3 doses. At the designated time a paracentesis will be performed at the start of the cataract procedure and at least 0.15 cc of aqueous humor will be collected. The sample will be immediately stored on dry ice and shipped to a laboratory for analysis.
NCT01001806 ↗ A Comparison of Peak Aqueous Penetration of Acuvail (Ketorolac 0.45%), Xibrom (Bromfenac 0.09%), and Nevanac (Nepafenac 0.1%)in Patients Undergoing Phacoemulsification Completed Frank A. Bucci, Jr., M.D. Phase 4 2009-10-01 Approximately 126 subjects scheduled to undergo cataract surgery by phacoemulsification, will be randomized in an even allocation (1:1:1) to either Acuvail, Xibrom, or Nevanac. Subjects will be instructed to begin dosing the study medication in the operative eye the day before surgery and continue dosing on the day of surgery. Beginning one hour before surgery, 1 drop of study medication will be instilled by operating room staff approximately every 15 minutes for a total of 3 doses. At the designated time a paracentesis will be performed at the start of the cataract procedure and at least 0.15 cc of aqueous humor will be collected. The sample will be immediately stored on dry ice and shipped to a laboratory for analysis.
NCT01021761 ↗ A Comparison of Prostaglandin E2 (PGE2) Inhibition of Acuvail(Ketorolac 0.45%), Xibrom (Bromfenac 0.09%)and Nevanac (Nepafenac)in Patients Undergoing Phacoemulsification Completed Allergan Phase 4 2009-10-01 Approximately 126 subjects scheduled to undergo cataract surgery by phacoemulsification, will be randomized in an even allocation (1:1:1) to either Acuvail, Xibrom or Nevanac. Subjects will be instructed to begin dosing the study medication in the operative eye the day before surgery and continue dosing on the day of surgery. Beginning one hour before surgery 1 drop of study medication will be instilled by operating room staff approximately every 15 minutes for a total of 3 doses. At the designated time a paracentesis will be performed at the start of the cataract procedure and at least 0.15cc of aqueous humor will be collected. The sample will be immediately stored on dry ice and shipped to a laboratory for analysis.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Acuvail

Condition Name

Condition Name for Acuvail
Intervention Trials
Cataracts 2
Diabetes Mellitus 1
Total Knee Arthroplasty 1
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Condition MeSH

Condition MeSH for Acuvail
Intervention Trials
Cataract 3
Macular Edema 2
Diabetic Retinopathy 2
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Clinical Trial Locations for Acuvail

Trials by Country

Trials by Country for Acuvail
Location Trials
United States 8
Malaysia 1
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Trials by US State

Trials by US State for Acuvail
Location Trials
Tennessee 2
Georgia 1
Massachusetts 1
New York 1
Minnesota 1
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Clinical Trial Progress for Acuvail

Clinical Trial Phase

Clinical Trial Phase for Acuvail
Clinical Trial Phase Trials
Phase 4 5
Phase 3 1
Phase 2 1
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Clinical Trial Status

Clinical Trial Status for Acuvail
Clinical Trial Phase Trials
Completed 6
Recruiting 2
Withdrawn 2
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Clinical Trial Sponsors for Acuvail

Sponsor Name

Sponsor Name for Acuvail
Sponsor Trials
Allergan 3
Frank A. Bucci, Jr., M.D. 2
Vanderbilt University 1
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Sponsor Type

Sponsor Type for Acuvail
Sponsor Trials
Other 12
Industry 3
NIH 2
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