The purpose of this study is to determine the safety of Nevanac 0.1% compared to Acular LS
0.4% and Vehicle in patients treated before cataract surgery and for approximately 90 days
following surgery.
Nepafenac Opthalmic Suspension 0.1% Compared to Acular LS for Treatment of Inflammation After Cataract Surgery
Completed
Alcon Research
Phase 3
2005-09-01
The purpose of this study is to compare the effectiveness of Nepafenac Ophthalmic Suspension,
0.1% eye drops to Acular LS eye drops, used before and after cataract surgery, for treating
inflammation in the eye.
Effect of Prophylactic Ketorolac on CME After Cataract Surgery
Completed
Queen's University
N/A
2006-06-01
The study will evaluate the efficacy of prophylactic administration of the topical
nonsteroidal anti-inflammatory drug (NSAID) ketorolac tromethamine 0.5% (Acular®) on cystoid
macular edema (CME) in patients having undergone cataract surgery. CME is the most frequent
cause of decreased vision after uncomplicated cataract surgery and can result in irreversible
sight reduction. The investigation will involve a comparison arm and a treatment arm with
both sets of patient populations being evaluated for CME with ophthalmologic examinations and
optical coherence tomography (OCT) measurements. The objective is to elucidate the role of
NSAID drops in preventing CME after cataract surgery.
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