CLINICAL TRIALS PROFILE FOR ACULAR LS

All Clinical Trials for Acular Ls

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00332774 ↗	Nevanac 3-Month Safety Study With QID Dosing	Completed	Alcon Research	Phase 3	2006-02-01	The purpose of this study is to determine the safety of Nevanac 0.1% compared to Acular LS 0.4% and Vehicle in patients treated before cataract surgery and for approximately 90 days following surgery.
NCT00333255 ↗	Nepafenac Opthalmic Suspension 0.1% Compared to Acular LS for Treatment of Inflammation After Cataract Surgery	Completed	Alcon Research	Phase 3	2005-09-01	The purpose of this study is to compare the effectiveness of Nepafenac Ophthalmic Suspension, 0.1% eye drops to Acular LS eye drops, used before and after cataract surgery, for treating inflammation in the eye.
NCT00335439 ↗	Effect of Prophylactic Ketorolac on CME After Cataract Surgery	Completed	Queen's University	N/A	2006-06-01	The study will evaluate the efficacy of prophylactic administration of the topical nonsteroidal anti-inflammatory drug (NSAID) ketorolac tromethamine 0.5% (Acular®) on cystoid macular edema (CME) in patients having undergone cataract surgery. CME is the most frequent cause of decreased vision after uncomplicated cataract surgery and can result in irreversible sight reduction. The investigation will involve a comparison arm and a treatment arm with both sets of patient populations being evaluated for CME with ophthalmologic examinations and optical coherence tomography (OCT) measurements. The objective is to elucidate the role of NSAID drops in preventing CME after cataract surgery.
NCT00347204 ↗	Comparison of Acular LS Versus Nevanac for Pain Control in Eyes Undergoing PRK	Completed	Allergan	Phase 4	2006-01-01	To determine the ability of two topical Nonsteroidal Anti-inflammatory drops (Acular LS & Nevanac) to help control pain following Photorefractive Keratectomy (PRK).
NCT00347204 ↗	Comparison of Acular LS Versus Nevanac for Pain Control in Eyes Undergoing PRK	Completed	Center For Excellence In Eye Care	Phase 4	2006-01-01	To determine the ability of two topical Nonsteroidal Anti-inflammatory drops (Acular LS & Nevanac) to help control pain following Photorefractive Keratectomy (PRK).
NCT00348244 ↗	Ketorolac vs. Steroid in the Prevention of CME	Completed	Innovative Medical	Phase 4	1969-12-31	Evaluate if the incidence of sub clinical CME can be significantly reduced by use of peri-operative Acular LS plus Pred Forte when compared with Pred Forte alone in normal cataract patients.
NCT00348582 ↗	Acular LS vs. Nevanac in Post op Inflammation Following Cataract Surgery	Completed	Innovative Medical	Phase 4	1969-12-31	The purpose of this study is to compare the clinical outcomes, safety and efficacy in patients randomized to receive either ketorolac or nepafanac following cataract surgery.

Clinical Trial Conditions for Acular Ls

Condition Name

Condition Name for Acular Ls
Intervention	Trials
Cataract	8
Renal Cell Carcinoma	1
Myopia	1
Retinal Detachment	1

Condition MeSH

Condition MeSH for Acular Ls
Intervention	Trials
Cataract	10
Inflammation	3
Glaucoma	2
Pain, Postoperative	2

Clinical Trial Locations for Acular Ls

Trials by Country

Trials by Country for Acular Ls
Location	Trials
United States	13
Canada	2
Croatia	2
Brazil	2
Greece	1

Trials by US State

Trials by US State for Acular Ls
Location	Trials
Arizona	2
Massachusetts	2
Texas	2
Georgia	1
Minnesota	1

Clinical Trial Progress for Acular Ls

Clinical Trial Phase

Clinical Trial Phase for Acular Ls
Clinical Trial Phase	Trials
Phase 4	13
Phase 3	3
Phase 2/Phase 3	1

Clinical Trial Status

Clinical Trial Status for Acular Ls
Clinical Trial Phase	Trials
Completed	18
Terminated	2
Withdrawn	1

Clinical Trial Sponsors for Acular Ls

Sponsor Name

Sponsor Name for Acular Ls
Sponsor	Trials
Innovative Medical	3
Mayo Clinic	3
Alcon Research	2

Sponsor Type

Sponsor Type for Acular Ls
Sponsor	Trials
Other	20
Industry	7