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Generated: April 25, 2019

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CLINICAL TRIALS PROFILE FOR ACETAMINOPHEN

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Clinical Trials for Acetaminophen

Trial ID Title Status Sponsor Phase Summary
NCT00000425 Toward Better Outcomes in Osteoarthritis Completed National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) Phase 3 This study will determine if there is a difference between commonly used nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen (a pain-reliever that does not prevent inflammation) for treating knee pain in osteoarthritis (OA). The two main results we will look at are disease progression according to x-rays and disability over 3.5 years. Study participants with moderate knee OA and knee pain will continue taking their NSAID or stop taking their NSAID and start taking acetaminophen. Every 6 months we will send the participants questionnaires that ask about pain, medication use, and disability. We will take x-rays of the knees at the start of the study and again at the end of the study.
NCT00000425 Toward Better Outcomes in Osteoarthritis Completed Stanford University Phase 3 This study will determine if there is a difference between commonly used nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen (a pain-reliever that does not prevent inflammation) for treating knee pain in osteoarthritis (OA). The two main results we will look at are disease progression according to x-rays and disability over 3.5 years. Study participants with moderate knee OA and knee pain will continue taking their NSAID or stop taking their NSAID and start taking acetaminophen. Every 6 months we will send the participants questionnaires that ask about pain, medication use, and disability. We will take x-rays of the knees at the start of the study and again at the end of the study.
NCT00000491 Aspirin-Myocardial Infarction Study (AMIS) Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 To determine whether the daily administration of 1 gm of aspirin to individuals with a documented myocardial infarction would result in a significant reduction in mortality over a three year period.
NCT00000713 A Phase I Clinical Trial To Evaluate the Toxicity, Antiviral and Immunomodulatory Effects of a Range of Doses of Ampligen in HIV-Infected Subjects Completed National Institute of Allergy and Infectious Diseases (NIAID) Phase 1 To determine the safety of ampligen at several doses in HIV-infected patients who have not yet developed AIDS or advanced AIDS related complex (ARC). Biologic, antiviral, and immunologic effects will be studied. Evidence indicates that a long period with no symptoms follows infection with HIV. Individuals who are infected with the virus could benefit from therapy with a drug that acts to kill the virus or to stimulate the immune system of the individual or both. The immune system is the means the human body has for fighting infections. Ampligen is a suitable drug for clinical trials against HIV because it has been shown to stimulate the immune system and to inhibit HIV in vitro (test tube) at drug levels that can be achieved without noticeable clinical side effects.
NCT00000731 Evaluation of the Interaction Between Acetaminophen and Zidovudine Completed National Institute of Allergy and Infectious Diseases (NIAID) N/A To determine if zidovudine (AZT) and acetaminophen (APAP) interact when given to the same patient, and if so, the manner of interaction. Patients with AIDS often require therapy with painkillers for the management of mild pain and discomfort associated with their disease, and APAP is often prescribed. AZT is being used to treat AIDS patients. It is important for doctors to understand how AZT and APAP may interact when given to the same patient, because other studies have suggested that the dosage of AZT may have to be adjusted when given with APAP in order to avoid or minimize adverse effects.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Acetaminophen

Condition Name

Condition Name for Acetaminophen
Intervention Trials
Pain 115
Pain, Postoperative 60
Postoperative Pain 42
Osteoarthritis 25
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Condition MeSH

Condition MeSH for Acetaminophen
Intervention Trials
Pain, Postoperative 150
Osteoarthritis 64
Acute Pain 36
Leukemia 33
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Clinical Trial Locations for Acetaminophen

Trials by Country

Trials by Country for Acetaminophen
Location Trials
Canada 79
United Kingdom 28
Korea, Republic of 12
France 12
Brazil 12
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Trials by US State

Trials by US State for Acetaminophen
Location Trials
Texas 139
New York 90
California 84
Pennsylvania 65
Ohio 61
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Clinical Trial Progress for Acetaminophen

Clinical Trial Phase

Clinical Trial Phase for Acetaminophen
Clinical Trial Phase Trials
Phase 4 288
Phase 3 151
Phase 2/Phase 3 21
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Clinical Trial Status

Clinical Trial Status for Acetaminophen
Clinical Trial Phase Trials
Completed 386
Recruiting 184
Not yet recruiting 138
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Clinical Trial Sponsors for Acetaminophen

Sponsor Name

Sponsor Name for Acetaminophen
Sponsor Trials
M.D. Anderson Cancer Center 48
Mallinckrodt 29
Merck Sharp & Dohme Corp. 15
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Sponsor Type

Sponsor Type for Acetaminophen
Sponsor Trials
Other 806
Industry 324
NIH 59
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