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Last Updated: October 21, 2019

DrugPatentWatch Database Preview

CLINICAL TRIALS PROFILE FOR ACALABRUTINIB

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Clinical Trials for Acalabrutinib

Trial ID Title Status Sponsor Phase Start Date Summary
NCT02029443 ACP-196 (Acalabrutinib), a Novel Bruton Tyrosine Kinase (Btk) Inhibitor, for Treatment of Chronic Lymphocytic Leukemia Active, not recruiting Acerta Pharma BV Phase 1/Phase 2 2014-01-01 This study is evaluating the safety and efficacy of a new Bruton tyrosine kinase (Btk) inhibitor, acalabrutinib, for the treatment of chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL)
NCT02157324 Acalabrutinib in Combination With ACP-319, for Treatment of Chronic Lymphocytic Leukemia Active, not recruiting Acerta Pharma BV Phase 1 2014-08-01 This study is evaluating the safety and efficacy of the combined use of acalabrutinib and ACP-319, for the treatment of chronic lymphocytic leukemia (CLL)
NCT02180711 An Open-label, Phase 1b Study of Acalabrutinib Alone or in Combination With Rituximab in Subjects With Follicular Lymphoma Active, not recruiting Acerta Pharma, LLC Phase 1 2014-07-01 To characterize the safety profile of acalabrutinib alone or in combination with rituximab in subjects with relapsed,refractory,or treatment naive Follicular Lymphoma (FL)
NCT02180711 An Open-label, Phase 1b Study of Acalabrutinib Alone or in Combination With Rituximab in Subjects With Follicular Lymphoma Active, not recruiting Acerta Pharma BV Phase 1 2014-07-01 To characterize the safety profile of acalabrutinib alone or in combination with rituximab in subjects with relapsed,refractory,or treatment naive Follicular Lymphoma (FL)
NCT02211014 An Open-Label, Phase 1b Study of Acalabrutinib With and Without Dexamethasone in Subjects With Multiple Myeloma Active, not recruiting Acerta Pharma, LLC Phase 1 2015-02-01 To characterize the safety profile of acalabrutinib with and without dexamethasone in subjects with relapsed or refractory Multiple Myeloma (MM)
NCT02211014 An Open-Label, Phase 1b Study of Acalabrutinib With and Without Dexamethasone in Subjects With Multiple Myeloma Active, not recruiting Acerta Pharma BV Phase 1 2015-02-01 To characterize the safety profile of acalabrutinib with and without dexamethasone in subjects with relapsed or refractory Multiple Myeloma (MM)
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Acalabrutinib

Condition Name

Condition Name for Acalabrutinib
Intervention Trials
Chronic Lymphocytic Leukemia 13
Small Lymphocytic Lymphoma 4
Mantle Cell Lymphoma 3
DLBCL 3
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Condition MeSH

Condition MeSH for Acalabrutinib
Intervention Trials
Leukemia, Lymphoid 16
Leukemia, Lymphocytic, Chronic, B-Cell 16
Lymphoma 15
Leukemia 13
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Clinical Trial Locations for Acalabrutinib

Trials by Country

Trials by Country for Acalabrutinib
Location Trials
United States 87
United Kingdom 7
Canada 4
Italy 3
Spain 2
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Trials by US State

Trials by US State for Acalabrutinib
Location Trials
Ohio 10
Washington 7
Texas 7
New York 7
Maryland 7
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Clinical Trial Progress for Acalabrutinib

Clinical Trial Phase

Clinical Trial Phase for Acalabrutinib
Clinical Trial Phase Trials
Phase 3 7
Phase 2/Phase 3 1
Phase 2 16
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Clinical Trial Status

Clinical Trial Status for Acalabrutinib
Clinical Trial Phase Trials
Not yet recruiting 16
Recruiting 12
Active, not recruiting 9
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Clinical Trial Sponsors for Acalabrutinib

Sponsor Name

Sponsor Name for Acalabrutinib
Sponsor Trials
Acerta Pharma BV 25
AstraZeneca 6
Merck Sharp & Dohme Corp. 4
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Sponsor Type

Sponsor Type for Acalabrutinib
Sponsor Trials
Industry 37
Other 19
NIH 5
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