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CLINICAL TRIALS PROFILE FOR ACALABRUTINIB

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All Clinical Trials for Acalabrutinib

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT02029443	ACP-196 (Acalabrutinib), a Novel Bruton Tyrosine Kinase (Btk) Inhibitor, for Treatment of Chronic Lymphocytic Leukemia	Active, not recruiting	Acerta Pharma BV	Phase 1/Phase 2	2014-01-01	This study is evaluating the safety and efficacy of a new Bruton tyrosine kinase (Btk) inhibitor, acalabrutinib, for the treatment of chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL)
NCT02157324	Acalabrutinib in Combination With ACP-319, for Treatment of Chronic Lymphocytic Leukemia	Active, not recruiting	Acerta Pharma BV	Phase 1	2014-08-01	This study is evaluating the safety and efficacy of the combined use of acalabrutinib and ACP-319, for the treatment of chronic lymphocytic leukemia (CLL)
NCT02180711	An Open-label, Phase 1b Study of Acalabrutinib Alone or in Combination With Rituximab in Subjects With Follicular Lymphoma	Active, not recruiting	Acerta Pharma, LLC	Phase 1	2014-07-01	To characterize the safety profile of acalabrutinib alone or in combination with rituximab in subjects with relapsed,refractory,or treatment naive Follicular Lymphoma (FL)
NCT02180711	An Open-label, Phase 1b Study of Acalabrutinib Alone or in Combination With Rituximab in Subjects With Follicular Lymphoma	Active, not recruiting	Acerta Pharma BV	Phase 1	2014-07-01	To characterize the safety profile of acalabrutinib alone or in combination with rituximab in subjects with relapsed,refractory,or treatment naive Follicular Lymphoma (FL)

Clinical Trial Conditions for Acalabrutinib

Condition Name

Condition Name for Acalabrutinib
Intervention	Trials
Chronic Lymphocytic Leukemia	14
Mantle Cell Lymphoma	5
Small Lymphocytic Lymphoma	4
DLBCL	3

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Condition MeSH

Condition MeSH for Acalabrutinib
Intervention	Trials
Lymphoma	20
Leukemia, Lymphoid	20
Leukemia, Lymphocytic, Chronic, B-Cell	20
Leukemia	17

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Clinical Trial Locations for Acalabrutinib

Trials by Country

Trials by Country for Acalabrutinib
Location	Trials
United States	94
United Kingdom	7
Canada	4
Spain	3
Italy	3

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Trials by US State

Trials by US State for Acalabrutinib
Location	Trials
Ohio	10
Texas	9
Washington	8
New York	8
Florida	7

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Clinical Trial Progress for Acalabrutinib

Clinical Trial Phase

Clinical Trial Phase for Acalabrutinib
Clinical Trial Phase	Trials
Phase 3	9
Phase 2/Phase 3	1
Phase 2	22

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Clinical Trial Status

Clinical Trial Status for Acalabrutinib
Clinical Trial Phase	Trials
Not yet recruiting	23
Recruiting	13
Active, not recruiting	9

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Clinical Trial Sponsors for Acalabrutinib

Sponsor Name

Sponsor Name for Acalabrutinib
Sponsor	Trials
Acerta Pharma BV	25
AstraZeneca	9
National Cancer Institute (NCI)	8

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Sponsor Type

Sponsor Type for Acalabrutinib
Sponsor	Trials
Industry	40
Other	26
NIH	9

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