The Effects of BCRP Q141K on Allopurinol Pharmacokinetics and Dynamics
Completed
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Phase 4
2016-11-01
Subjects will undergo a placebo and allopurinol phase to better understand the effects of the
reduced function BCRP Q141K variant on allopurinol pharmacokinetics and pharmacodynamics.
The Effects of BCRP Q141K on Allopurinol Pharmacokinetics and Dynamics
Completed
Open Medicine Institute
Phase 4
2016-11-01
Subjects will undergo a placebo and allopurinol phase to better understand the effects of the
reduced function BCRP Q141K variant on allopurinol pharmacokinetics and pharmacodynamics.
The Effects of BCRP Q141K on Allopurinol Pharmacokinetics and Dynamics
Completed
University of California, San Francisco
Phase 4
2016-11-01
Subjects will undergo a placebo and allopurinol phase to better understand the effects of the
reduced function BCRP Q141K variant on allopurinol pharmacokinetics and pharmacodynamics.
Chemotherapy in Patients With Relapsed Small Cell Lung Cancer in Combination With Allopurinol and MycoPhenolate (CLAMP Trial)
Not yet recruiting
Washington University School of Medicine
Phase 1/Phase 2
2022-03-31
The hypothesis is that the addition of mycophenolate mofetil (MMF) and allopurinol to
chemotherapy in patients with relapsed small cell lung cancer (SCLC) will be safely tolerated
and improve outcomes, as measured by response rate and progression-free survival in patients
compared to other single agent chemotherapy drugs used in historical controls.
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