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Last Updated: March 28, 2024

CLINICAL TRIALS PROFILE FOR ALBUTEROL SULFATE; IPRATROPIUM BROMIDE


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All Clinical Trials for ALBUTEROL SULFATE; IPRATROPIUM BROMIDE

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00462540 ↗ A Crossover Study in the Treatment of Patients With COPD Completed Dey Phase 3 2007-05-01 The purpose of this study is to compare the efficacy of Formoterol Fumarate Inhalation Solution (FFIS) 20 mcg BID to Combivent® Inhalation Aerosol [2 inhalations from metered dose inhaler (MDI)of 18 mcg ipratropium bromide and 103 mcg albuterol sulfate QID], and to Compare the preference/compliance of BID nebulization to QID use of MDI
NCT01515995 ↗ Nebulized Magnesium Sulfate in Children With Moderate to Severe Asthma Exacerbation Completed University of Texas Southwestern Medical Center Phase 4 2012-01-01 The purpose of this study is to evaluate the effectiveness of nebulized magnesium sulfate as a vehicle for albuterol in children with moderate to severe asthma exacerbation.
NCT02182674 ↗ A Confirmation Study of Combivent HFA Inhalation Aerosol in Patients With Chronic Obstructive Pulmonary Disease (COPD) Completed Boehringer Ingelheim Phase 2 2000-10-01 Study to demonstrate the comparability of two puffs of Combivent hydrofluoroalkane (HFA) inhalation aerosol (18 mcg ipratropium bromide/100 mcg albuterol sulfate / per puff) to two puffs of the marketed chlorofluorocarbon (CFC) containing product, Combivent (CFC) inhalation aerosol (18 mcg ipratropium bromide/103 mcg albuterol sulfate / per puff). The dose response profile, safety and pharmacokinetics of Combivent HFA formulation are to be characterized.
NCT02586649 ↗ 24hr Effects of Tiotropium Bromide in Tetraplegia Completed James J. Peters Veterans Affairs Medical Center Phase 2 2014-07-01 Respiratory complications are the leading cause of death during the initial year after acute SCI, and the third leading cause of death thereafter. Complete or partial loss of respiratory muscle innervations in individuals with cervical and high thoracic injuries leads to inadequate ventilation and inability to effectively clear secretions, often prompting supportive ventilation following initial injury. Development of atelactasis, pneumonias and respiratory failure are the most common respiratory complications observed during the acute phase of injury. It is well known that a restrictive ventilatory defect, dependent upon the level and completeness of injury, is apparent in individuals with chronic cervical SCI. Respiratory functional impairment might be further compromised in these individuals, the majority of whom share many aspects of obstructive airway physiology commonly associated with asthma. The asthma-like features that individuals with chronic cervical SCI demonstrate have been hypothesized to be due to overriding cholinergic airway tone carried by intact vagal (parasympathetic) nerve fibers arising from the brainstem, whereas sympathetic innervations is interrupted at the level of the upper thoracic spinal cord. Whether airway narrowing and AHR in chronic cervical SCI is also related to chronic airway inflammation is unknown, although it is conceivable that repeated respiratory infections or, possibly, a neurogenic component, could contribute to chronic airway inflammation. Therefore, the investigators aim to assess how long-acting bronchodilator (tiotropium bromide) affects various indices of lung function, including: pulmonary function tests, levels of inflammation and cough strength across 24 hours after receiving study drug. Results will be analyzed for baseline, 1 hour, 3 hours, 20 hours and 24 hours post drug inhalation for both active medication and non-active placebo.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for ALBUTEROL SULFATE; IPRATROPIUM BROMIDE

Condition Name

Condition Name for ALBUTEROL SULFATE; IPRATROPIUM BROMIDE
Intervention Trials
Chronic Obstructive Pulmonary Disease 1
Pulmonary Disease, Chronic Obstructive 1
Spinal Cord Injury 1
Asthma 1
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Condition MeSH

Condition MeSH for ALBUTEROL SULFATE; IPRATROPIUM BROMIDE
Intervention Trials
Pulmonary Disease, Chronic Obstructive 2
Lung Diseases 2
Asthma 1
Lung Diseases, Obstructive 1
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Clinical Trial Locations for ALBUTEROL SULFATE; IPRATROPIUM BROMIDE

Trials by Country

Trials by Country for ALBUTEROL SULFATE; IPRATROPIUM BROMIDE
Location Trials
United States 14
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Trials by US State

Trials by US State for ALBUTEROL SULFATE; IPRATROPIUM BROMIDE
Location Trials
Texas 2
New York 1
West Virginia 1
Washington 1
Tennessee 1
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Clinical Trial Progress for ALBUTEROL SULFATE; IPRATROPIUM BROMIDE

Clinical Trial Phase

Clinical Trial Phase for ALBUTEROL SULFATE; IPRATROPIUM BROMIDE
Clinical Trial Phase Trials
Phase 4 1
Phase 3 1
Phase 2 2
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Clinical Trial Status

Clinical Trial Status for ALBUTEROL SULFATE; IPRATROPIUM BROMIDE
Clinical Trial Phase Trials
Completed 4
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Clinical Trial Sponsors for ALBUTEROL SULFATE; IPRATROPIUM BROMIDE

Sponsor Name

Sponsor Name for ALBUTEROL SULFATE; IPRATROPIUM BROMIDE
Sponsor Trials
Dey 1
University of Texas Southwestern Medical Center 1
Boehringer Ingelheim 1
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Sponsor Type

Sponsor Type for ALBUTEROL SULFATE; IPRATROPIUM BROMIDE
Sponsor Trials
Industry 2
Other 1
U.S. Fed 1
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