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Last Updated: April 19, 2024

CLINICAL TRIALS PROFILE FOR ACIPHEX


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All Clinical Trials for ACIPHEX

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00204672 ↗ The Role of GER in Exercise Triggered Asthma Completed PriCara, Unit of Ortho-McNeil, Inc. Phase 2/Phase 3 2000-10-01 HYPOTHESIS Gastroesophageal reflux is a major contributor to exercise-triggered asthma. Two groups of patients will be studied: those with asthma who have difficulty with exertion, those without asthma who experience difficulty with exertion. Both groups will experience gastroesophageal reflux (GER) twice of less per week. Patients will complete a treadmill exam to determine their VO2 max. They will then undergo pH monitoring while exercising for 30 minutes at 65-70% of their VO2 max. Subjects will be given placebo or acid suppression pill for 12 weeks. At the end of 12 weeks, the subjects will repeat the exercise (30 minutes) and 24-hour pH study.
NCT00204672 ↗ The Role of GER in Exercise Triggered Asthma Completed University of Utah Phase 2/Phase 3 2000-10-01 HYPOTHESIS Gastroesophageal reflux is a major contributor to exercise-triggered asthma. Two groups of patients will be studied: those with asthma who have difficulty with exertion, those without asthma who experience difficulty with exertion. Both groups will experience gastroesophageal reflux (GER) twice of less per week. Patients will complete a treadmill exam to determine their VO2 max. They will then undergo pH monitoring while exercising for 30 minutes at 65-70% of their VO2 max. Subjects will be given placebo or acid suppression pill for 12 weeks. At the end of 12 weeks, the subjects will repeat the exercise (30 minutes) and 24-hour pH study.
NCT00204698 ↗ Laryngopharyngeal Reflux and Proton Pump Inhibitor (PPI) Treatment Completed PriCara, Unit of Ortho-McNeil, Inc. Phase 2/Phase 3 2003-08-01 This study proposes to investigate prospectively, the presence of molecular markers for inflammation in laryngopharyngeal reflux (LPR) patients and to study the effect of a proton pump inhibitor (Aciphex) on these molecular markers. The investigators will be evaluating a group of patients before and after treatment. This group will be patients that have untreated laryngopharyngeal reflux diagnosed by laryngoscopic assessment and a 24-hour probe.
NCT00204698 ↗ Laryngopharyngeal Reflux and Proton Pump Inhibitor (PPI) Treatment Completed University of Utah Phase 2/Phase 3 2003-08-01 This study proposes to investigate prospectively, the presence of molecular markers for inflammation in laryngopharyngeal reflux (LPR) patients and to study the effect of a proton pump inhibitor (Aciphex) on these molecular markers. The investigators will be evaluating a group of patients before and after treatment. This group will be patients that have untreated laryngopharyngeal reflux diagnosed by laryngoscopic assessment and a 24-hour probe.
NCT00236184 ↗ E3810-A001-313: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers Completed Eisai Inc. Phase 3 2005-10-01 The purpose of this study is to investigate the safety and efficacy of rabeprazole sodium 10 mg in treating frequent heartburn.
NCT00236197 ↗ E3810-A001-312: Efficacy and Safety of 10 mg Rabeprazole for Treating Heartburn in Frequent Sufferers Completed Eisai Inc. Phase 3 2005-10-01 The purpose of this study is to investigate the safety and efficacy of rabeprazole 10 mg in treating frequent heartburn.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for ACIPHEX

Condition Name

Condition Name for ACIPHEX
Intervention Trials
Healthy 7
Gastroesophageal Reflux Disease (GERD) 6
Heartburn 2
Laryngopharyngeal Reflux 2
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Condition MeSH

Condition MeSH for ACIPHEX
Intervention Trials
Gastroesophageal Reflux 12
Esophagitis, Peptic 7
Heartburn 2
Laryngopharyngeal Reflux 2
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Clinical Trial Locations for ACIPHEX

Trials by Country

Trials by Country for ACIPHEX
Location Trials
United States 55
Japan 24
India 16
Germany 13
Argentina 10
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Trials by US State

Trials by US State for ACIPHEX
Location Trials
Illinois 5
California 5
North Dakota 4
New York 3
Connecticut 2
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Clinical Trial Progress for ACIPHEX

Clinical Trial Phase

Clinical Trial Phase for ACIPHEX
Clinical Trial Phase Trials
Phase 4 1
Phase 3 8
Phase 2/Phase 3 4
[disabled in preview] 9
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Clinical Trial Status

Clinical Trial Status for ACIPHEX
Clinical Trial Phase Trials
Completed 21
Terminated 1
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Clinical Trial Sponsors for ACIPHEX

Sponsor Name

Sponsor Name for ACIPHEX
Sponsor Trials
Eisai Inc. 9
Mylan Pharmaceuticals 3
Torrent Pharmaceuticals Limited 2
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Sponsor Type

Sponsor Type for ACIPHEX
Sponsor Trials
Industry 23
Other 5
U.S. Fed 2
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