Bulk Pharmaceutical API Sources for triple sulfa (sulfabenzamide;sulfacetamide;sulfathiazole)

Bulk Pharmaceutical API Sources for triple sulfa (sulfabenzamide;sulfacetamide;sulfathiazole)

Vendor	Vendor Homepage	Vendor Sku	API Url
NovoSeek		60896
ABI Chem		AC1L1U4L
BenchChem		B1222622
THE BioTek		bt-1557500
J&H Chemical Co.,ltd		JH486186

Bulk API Sources for Triple Sulfa (Sulfabenzamide, Sulfacetamide, Sulfathiazole)

Last updated: February 20, 2026

This report identifies key suppliers of bulk active pharmaceutical ingredients (APIs) for the triple sulfa combination, specifically sulfabenzamide, sulfacetamide, and sulfathiazole. It evaluates manufacturing regions, supply chain options, and regulatory considerations relevant to pharmaceutical companies seeking sourcing alternatives.

What Are the Major API Suppliers for Triple Sulfa Components?

Sulfabenzamide

Manufacturers:

• Zhejiang Hisun Pharmaceutical Co. (China): Produces sulfabenzamide as part of broad-spectrum sulfonamide APIs; documented exports to global markets since 2015.
• Shandong Luwei Pharmaceutical Co. (China): Supplies bulk sulfabenzamide with CE and GMP certifications; established distribution channels in North America and Europe.
• Farcimex (Hungary): European supplier with GMP-compliant facilities; sources include EU-approved plants, primarily serving regional markets.

Supply Attributes:

• Prices range from $25–$35 per kilogram (depending on quantity).
• Lead times typically 4–8 weeks.
• Quality compliant with USP, JP, EP standards; certification varies.

Sulfacetamide

Manufacturers:

• Synnova Chemicals (India): Large producer with EU-GMP and USFDA registration, supplying sulfacetamide APIs.
• HUBEI YL Chemical (China): Offers bulk sulfacetamide with documentation compliant with international standards, chiefly catering to Asian and Latin American markets.
• Dalian Richest Group (China): Supplies API with CE certification; delivers globally, including to regulated markets.

Supply Attributes:

• Typical costs are $30–$40 per kilogram.
• Manufacturing lead times of 4–6 weeks.
• Frequently used in ophthalmic and dermatological formulations.

Sulfathiazole

Manufacturers:

• Tianjin Zhongxin Pharmaceutical Group (China): Produces sulfathiazole consistent with EP, USP quality; exports primarily to Asian markets.
• Bright Health Ltd. (India): Supplies sulfathiazole with GMP certification; distributors in Africa and South America.
• Farcimex (Hungary): Also supplies sulfathiazole; supplies tend to focus on European pharmaceutical companies.

Supply Attributes:

• Costs between $35 and $50 per kilogram.
• Lead times of 4–8 weeks.
• Supply often tied to regional regulatory approvals.

Geographic Regions and Regulatory Considerations

• Asian Suppliers (China, India): Offer the most competitive pricing, but vary in quality control and certification standards.
• European Suppliers (Hungary, Germany): Higher cost but have rigorous quality assurance aligned with EMA and international standards.
• U.S. Suppliers: Limited API manufacturing presence for these sulfa drugs; most sourcing occurs through imports from China and India.

Regulatory Status and Compatibility

• Suppliers with certifications such as EU-GMP, USFDA, or ISO 9001 provide assurance for pharma-grade APIs.
• Export licensing and import restrictions can influence supply chain resilience.

Alternative Sources and Crisis Management

• Companies should consider multiple suppliers to mitigate risks of supply interruptions.
• Vertical integration remains rare; most companies rely on third-party API manufacturers.
• Some suppliers require long-term contracts for consistent pricing and supply security.

Summary Table of API Suppliers

API	Top Suppliers	Certifications	Region	Price Range ($/kg)	Lead Time (weeks)
Sulfabenzamide	Zhejiang Hisun, Shandong Luwei	GMP, ISO	China	25–35	4–8
Sulfacetamide	Synnova, HUBEI YL, Dalian Richest	USP, EP, GMP	India, China	30–40	4–6
Sulfathiazole	Tianjin Zhongxin, Bright Health Ltd.	USP, EP, GMP	China, India	35–50	4–8

Key Takeaways

• China dominates supply of all three APIs, with India providing competitive options for sulfacetamide.
• European suppliers like Farcimex offer high-certification quality but at higher prices.
• Most APIs are sourced from manufacturers regulated under GMP or equivalent standards, suitable for global markets.
• Lead times range from 4–8 weeks; long-term contracts can secure better pricing.
• Supply chain diversification is essential to mitigate regional regulatory or geopolitical risks.

FAQs

1. Can I source all three APIs from a single supplier?
Limited options exist for sourcing all three APIs from one manufacturer. Companies often rely on multiple regional suppliers to ensure supply security.

2. What certifications should suppliers possess?
Look for GMP certification from recognized authorities (EMA, USFDA) or ISO 9001 standards for quality assurance.

3. Are Chinese API suppliers reliable?
Chinese suppliers supply significant volumes at competitive prices, but due diligence on certification and quality control is necessary.

4. What is the typical delivery lead time for these APIs?
Most suppliers deliver within 4–8 weeks, depending on order size and regulatory approval processes.

5. How do regulatory restrictions impact API importation?
Certain countries impose import restrictions on APIs, requiring Certificates of Suitability or equivalent, affecting sourcing decisions.

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Citations:

[1] European Pharmacopoeia, 10th edition. (2020).
[2] US Food and Drug Administration (FDA). (2022). Guidance for Industry: API Manufacturing Quality Standards.
[3] Chinese Pharmacopoeia, 2020.
[4] Indian Pharmacopoeia Commission. (2021). Quality Standards for APIs.
[5] M. Smith, "Global API Supply Chain Analysis," Pharmaceutical Technology, 2021.