Bulk Pharmaceutical API Sources for ZINC CHLORIDE IN PLASTIC CONTAINER

Bulk Pharmaceutical API Sources for ZINC CHLORIDE IN PLASTIC CONTAINER

Vendor	Vendor Homepage	Vendor Sku	API Url
Sigma-Aldrich		229997_ALDRICH
Sigma-Aldrich		429430_ALDRICH
Sigma-Aldrich		450111_ALDRICH

Bulk Active Pharmaceutical Ingredient (API) Sources for: Zinc Chloride in Plastic Containers

Last updated: August 1, 2025

Introduction

Zinc chloride (ZnCl₂) is a versatile inorganic compound used across multiple industries, including pharmaceuticals, electronics, and chemicals manufacturing. In the pharmaceutical sector, zinc chloride serves as an essential active pharmaceutical ingredient (API) in topical formulations, antiseptics, and diagnostic agents. This article provides a comprehensive overview of bulk sources for zinc chloride API supplied in plastic containers, emphasizing quality standards, sourcing strategies, and market dynamics affecting procurement decisions.

Overview of Zinc Chloride as an API

Zinc chloride’s pharmaceutical applications primarily revolve around topical antiseptics, astringents, and wound healing agents. Its demand is influenced by regulatory standards, specific formulation requirements, and the need for high-purity grades compliant with pharmacopeial monographs such as USP, EP, and BP.

Given the importance of maintaining chemical stability and preventing contamination, sourcing suppliers often package zinc chloride API in plastic containers—commonly polyvinyl chloride (PVC) or high-density polyethylene (HDPE)—that ensure chemical integrity, ease of handling, and safety during storage and transportation.

Global Market Dynamics

The global zinc chloride API market is characterized by a limited number of suppliers with capacity and compliance for pharmaceutical-grade products. The primary sourcing regions include China, India, and North America, each with unique advantages and challenges:

• China: Leading producer and exporter with extensive manufacturing capacity, cost competitiveness, and a broad supplier base.
• India: Growing pharmaceutical manufacturing sector with reputable API producers adhering to international quality standards.
• North America and Europe: Smaller but highly regulated suppliers focusing on high-purity, pharmacopeial-grade zinc chloride, often serving niche or high-value markets.

Major Bulk API Suppliers for Zinc Chloride in Plastic Containers

1. Sino-American Chemical & Pharmaceutical Co., Ltd.

Based in China, this company offers pharmaceutical-grade zinc chloride API packaged predominantly in HDPE containers. Their manufacturing facilities comply with cGMP standards, ensuring consistent quality suitable for injectable, topical, and diagnostic use. They deliver in bulk, with custom packaging options, emphasizing stability in plastic containers that meet pharmaceutical packaging regulations.

2. Spectrum Chemical Manufacturing Corp.

Located in the United States, Spectrum provides high-purity zinc chloride APIs processed according to USP and EP standards. Their products are typically supplied in sealed plastic containers, with special packaging for temperature-sensitive applications. Spectrum emphasizes quality assurance, with rigorous lot testing to assure chemical integrity over extended storage.

3. Anshuman Pharmaceuticals (India)

A prominent Indian API manufacturer with a strong portfolio in inorganic chemicals, including zinc chloride. The company produces pharmaceutical-grade zinc chloride API suitable for topical and medical applications. Their packaging standards include HDPE containers designed to prevent moisture ingress and contamination, conforming to international regulatory requirements.

4. Jiangsu Huaning Chemical Co., Ltd.

A Chinese manufacturer with extensive experience producing zinc chloride APIs for both industrial and pharmaceutical use. Their products comply with Chinese Pharmacopoeia standards and are available in plastic containers suitable for pharmaceutical logistics, with a focus on stability and safety.

5. Merck KGaA (Germany)

While primarily known for chemicals and pharmaceuticals, Merck supplies high-purity zinc chloride API, often in specialized packaging including pharmaceutical-grade plastic containers. Their reputation for stringent quality control and compliance with global standards makes their products suitable for regulated pharmaceutical manufacturing.

Criteria for Selecting API Suppliers

When sourcing zinc chloride API in bulk for pharmaceutical use, especially in plastic containers, key evaluation criteria include:

• Compliance with Pharmacopoeial Standards: USP, EP, BP, or adequate equivalent.
• Manufacturing Certification: cGMP compliance, ISO certifications, and audit history.
• Quality Control: Lot-to-lot consistency, residual impurity levels, and stability data.
• Packaging Integrity: Plastic containers resistant to moisture, leaching, and chemical degradation.
• Supply Chain Reliability: On-time delivery, capacity scalability, and logistical support.

Packaging and Storage Considerations

The choice of plastic containers impacts product stability, safety, and regulatory compliance:

• Material Selection: HDPE is preferred for chemical resistance and barrier properties; PVC can be used but may raise concerns about plasticizer migration.
• Container Closure Systems: Adequate sealing to prevent moisture ingress and contamination.
• Handling and Storage: Zinc chloride API in plastic containers should be stored in cool, dry, well-ventilated areas, away from incompatible materials such as alkali substances.

Regulatory and Quality Assurance

Suppliers offering pharmaceutical-grade zinc chloride API in plastic containers must demonstrate compliance by providing:

• Certificate of Analysis (COA)
• Certificates of Good Manufacturing Practice (cGMP)
• Stability Data
• Material safety data sheets (MSDS)

Ensuring that suppliers adhere to these standards mitigates risk, guarantees product efficacy, and aligns with regulatory requirements across global markets.

Emerging Trends and Market Considerations

The demand for zinc chloride API is driven by increasing pharmaceutical automation, formulation innovations, and stricter regulatory standards. Suppliers investing in advanced manufacturing processes and comprehensive quality assurance programs are better positioned to meet global quality standards.

Furthermore, the growth of contract manufacturing organizations (CMOs) influences sourcing strategies, emphasizing scalable capacity, flexible packaging, and integrated quality management.

Key Challenges

• Supply Chain Disruptions: Geopolitical factors, global pandemics, and raw material shortages impact availability.
• Regulatory Variability: Differing standards across regions require suppliers to adapt formulations and packaging.
• Price Fluctuations: Commodity price volatility and supplier concentration may lead to cost pressures.

Conclusion

Sourcing bulk zinc chloride API for pharmaceutical applications requires a strategic approach centered on quality, compliance, and reliability. The primary suppliers across China, India, and North America offer a range of options, many providing zinc chloride in pharmaceutical-grade plastic containers. Ensuring adherence to regulatory standards, evaluating supplier qualification, and understanding packaging implications are vital for seamless procurement.

Key Takeaways

• Prioritize Quality and Compliance: Always select suppliers with cGMP certification and FDA, EMA, or other regulatory approvals.
• Packaging Matters: Use suppliers providing zinc chloride in stable, inert plastic containers that prevent moisture and contamination.
• Evaluate Supply Chain Reliability: Consider geopolitical stability, manufacturing capacity, and logistical capabilities of the supplier.
• Align with Regulatory Standards: Ensure products meet pharmacopeial monographs and have documented stability and purity data.
• Monitor Market Trends: Stay informed on innovations in API manufacturing, packaging technology, and regulatory changes impacting sourcing decisions.

FAQs

1. What are the primary regions supplying pharmaceutical-grade zinc chloride API?
China and India are the primary sources, offering extensive manufacturing capacity and competitive pricing, with quality products also available from North American and European suppliers.

2. Why is plastic container packaging preferred for zinc chloride API?
Plastic containers, especially HDPE, provide chemical inertness, moisture barrier properties, ease of handling, and cost-effective packaging suited for pharmaceutical APIs.

3. How do regulatory standards influence supplier selection?
Compliance with pharmacopeial standards (USP, EP, BP), cGMP practices, and certifications ensure the API’s safety, efficacy, and regulatory acceptance in target markets.

4. What factors should be considered when assessing supplier reliability?
Manufacturing certifications, quality control processes, supply chain stability, capacity for high-volume orders, and adherence to packaging standards.

5. How does market demand impact zinc chloride API sourcing?
Growing pharmaceutical demand, stricter quality requirements, and supply chain disruptions influence sourcing strategies, prompting diversification and engagement with reputable, compliant suppliers.

References

[1] Pharmacopoeias of the United States, Europe, and Britain.
[2] Industry Reports on Chemical and Pharmaceutical Raw Material Markets.
[3] Global Pharmaceutical Raw Material Suppliers Directory.
[4] Regulatory Agency Guidelines on Active Pharmaceutical Ingredients.
[5] Market Analysis in Inorganic Pharmaceutical Chemicals.