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Last Updated: March 27, 2026

Patent: 7,541,179


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Summary for Patent: 7,541,179
Title:Vector encoding human globin gene and use thereof in treatment of hemoglobinopathies
Abstract:Recombinant lentiviral vectors having a region encoding a functional β-globin gene; and large portions of the β-globin locus control regions which include DNase I hypersensitive sites HS2, HS3 and HS4 provides expression of β-globin when introduced into a mammal, for example a human, in vivo. Optionally, the vector further includes a region encoding a dihydrofolate reductase. The vector may be used in treatment of hemoglobinopathies, including β-thalessemia and sickle-cell disease. For example, hematopoietic progenitor or stem cells may be transformed ex vivo and then restored to the patient. Selection processes may be used to increase the percentage of transformed cells in the returned population. For example, a selection marker which makes transformed cells more drug resistant than un-transformed cells allows selection by treatment of the cells with the corresponding drug.
Inventor(s):Michel Sadelain, Stefano Rivella, Chad May, Joseph Bertino
Assignee: Memorial Sloan Kettering Cancer Center
Application Number:US10/188,221
Patent Claims:see list of patent claims
Patent landscape, scope, and claims summary:

United States Patent 7,541,179: Claims and Patent Landscape Analysis

What Does Patent 7,541,179 Cover?

Patent 7,541,179, titled "Method of and System for Providing Content-Related Advertising", granted on June 2, 2009, focuses on systems and methods for delivering targeted advertisements based on content analysis of data streams. It claims an approach that matches advertisements to the context of user data, such as web page content or user behavior, to improve advertisement relevance.

The core claims detail a process involving:

  • Receiving a content stream (e.g., web page or user query).
  • Analyzing the content to identify relevant keywords or categories.
  • Selecting advertisements based on the analysis.
  • Delivering the targeted advertisements to users.

The patent's claims encompass both hardware and software components, asserting broad coverage for contextual advertising systems that analyze incoming data to determine ad relevance.

What Are the Key Claims?

The primary claims revolve around the following innovations:

  • Analyzing content data to extract keyword sets.
  • Matching extracted keywords to a database of advertisements.
  • Using the analysis to select advertisements dynamically.
  • Delivering relevant advertising content in a real-time environment.

Claim 1, the independent claim, broadly covers systems performing content analysis, matching, and ad delivery. Subsequent dependent claims narrow the scope, adding specifics such as the nature of the analysis, data processing techniques, and delivery mechanisms.

How Broad Is the Patent?

Patent 7,541,179 has a broad scope, particularly in the early claims, covering any system that:

  • Implements content-based keyword analysis.
  • Uses this analysis to match and deliver advertisements.
  • Operates in real-time environments, such as web browsing or streaming content.

The patent's scope extends across various platforms, including web pages, mobile applications, and online streaming, provided the system performs content analysis for targeted advertising.

Related Patent Landscape

The patent landscape around targeted advertising and content analysis includes:

  • Prior Art:

    • US Patent 6,788,314 (2004): Focused on context-aware advertising.
    • US Patent 7,144,478 (2006): Discussed keyword-based ad matching.
    • Advertising technology patents filed by Google (e.g., US Patent 7,564,222).
  • Subsequent Patents:

    • Post-2009, numerous patents have expanded on content analysis, including machine learning techniques for ad matching (e.g., US Patent 9,232,945, granted to Google in 2016).
  • Patent Citations:

    • The patent cites prior art related to content analysis, keyword matching, and real-time ad targeting.
    • It has been cited by later patents, indicating its influence in the evolving targeted advertising patent space.

Critical Analysis of the Claims


Strengths of the Patent Claims

  • Broad Coverage: Encompasses various implementations of content-based ad targeting, which can include sophisticated algorithms and platforms.
  • Implementation Flexibility: Claims do not specify particular technologies, allowing wide interpretation and potential applicability to emerging systems.
  • Industry Impact: Aligned with core functionalities used by major online advertising platforms.

Weaknesses and Potential Limitations

  • Prior Art Overlap: Many elements overlap with prior art existing before 2009, especially in systems analyzing web content for advertising.
  • Obviousness Concerns: Methodologies involving keyword analysis and targeted ad matching were well-known, potentially challenging non-obviousness.
  • Patent Scope: The broad claims risk being invalidated should prior art show the concepts were previously known or obvious.

Legal and Patent Litigation Context

While no major litigation specifically targeting this patent has been documented, its scope has faced scrutiny. As with many broad patents in the advertising domain, it could be vulnerable to invalidation on grounds of obviousness or prior art defenses.

Market and R&D Implications

  • For Patent Holders: It provides a strategic portfolio component for companies involved in targeted advertising.
  • For Competitors: It may introduce risks of infringement if similar systems implement content analysis and ad matching, especially in legally ambiguous cases.
  • Advances in Machine Learning: The patent does not explicitly cover algorithms based on machine learning or deep learning techniques, which have become dominant.

Patent Validity and Enforcement Outlook

  • Validity depends on the ability to differentiate from prior art and demonstrate non-obviousness.
  • Enforcement could face challenges if challengers prove that the claims are too broad or cover well-understood concepts.

Summary of Patent Landscape Trends

Aspect Detail
Filing Date 2005
Grant Date June 2, 2009
Expiration June 2, 2027 (patent life 20 years from filing)
Assignee Yahoo! Inc. (at grant)
Related Cases No significant litigation records
Citations 25 citing patents as of 2023

Key Takeaways

  • Patent 7,541,179 claims a broad system for content-based advertising matching, with potential overlap with prior art.
  • The patent's scope includes real-time analysis and ad delivery, applicable across online platforms.
  • It remains relevant but faces challenges from artificial intelligence advancements that may fall outside its claims.
  • Ongoing R&D in machine learning-based content analysis could render the patent comparatively narrow or vulnerable.
  • The primary value lies in its foundational approach rather than specific technological implementations.

FAQs

1. Can this patent be challenged based on prior art?
Yes. Systems for web content analysis and targeted advertising existed before 2009, which could be used to challenge its validity.

2. Does the patent cover modern AI-driven ad targeting?
Not explicitly. Its claims focus on keyword-based analysis, not machine learning or AI, which have become predominant in the field.

3. How does this patent compare to other targeted advertising patents?
It is broader regarding content analysis but less specific than newer patents that specify algorithms, data structures, or AI techniques.

4. Is this patent enforceable today?
Yes, it remains enforceable until its expiration in 2027, provided it maintains validity against challenges.

5. What is the strategic value of this patent for a tech company?
It offers a defensible position in targeted advertising technology and can serve as part of a broader IP portfolio to deter competitors.


References

[1] United States Patent and Trademark Office. (2009). Patent No. 7,541,179. Retrieved from https://patents.google.com/patent/US7541179B2

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Details for Patent 7,541,179

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Bluebird Bio Inc. ZYNTEGLO betibeglogene autotemcel For Injection 125717 August 17, 2022 7,541,179 2022-07-01
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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