Patent: 5,935,566
✉ Email this page to a colleague
Summary for Patent: 5,935,566
Title: | Stable aqueous alfa interferon solution formulations |
Abstract: | Stable aqueous solution formulations containing alfa-interferon type interferon, e.g., interferon alfa-2a and interferon alfa-2b, a buffer to maintain the pH in the range of 4.5-7.1, polysorbate 80 as a stabilizer, edetate disodium as a chelating agent, sodium chloride as a tonicity agent, and m-cresol as an antimicrobial preservative and which maintain high chemical, physical and biological stability of the alfa-type interferon for an extended storage period of at least 24 months are disclosed. |
Inventor(s): | Yuen; Pui-Ho C. (Princeton Junction, NJ), Kline; Douglas F. (Hoboken, NJ) |
Assignee: | Schering Corporation (Kenilworth, NJ) |
Application Number: | 09/096,708 |
Patent Claims: | see list of patent claims |
Details for Patent 5,935,566
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | For Injection | 103132 | 06/04/1986 | ⤷ Try a Trial | 2014-10-11 |
Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | For Injection | 103132 | ⤷ Try a Trial | 2014-10-11 | |
Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | Injection | 103132 | ⤷ Try a Trial | 2014-10-11 | |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
International Patent Family for US Patent 5,935,566
Country | Patent Number | Estimated Expiration |
---|---|---|
Austria | 194774 | ⤷ Try a Trial |
Austria | 245033 | ⤷ Try a Trial |
Australia | 3727995 | ⤷ Try a Trial |
Australia | 708337 | ⤷ Try a Trial |
Brazil | 9509313 | ⤷ Try a Trial |
>Country | >Patent Number | >Estimated Expiration |