Patent: 10,610,605
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Summary for Patent: 10,610,605
Title: | Nucleic acid comprising or coding for a histone stem-loop and a poly(A) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein |
Abstract: | Provided herein are nucleic acid sequences, comprising or coding for a coding region, encoding at least one peptide or protein comprising a therapeutic protein or a fragment, variant or derivative thereof. Furthermore the use of the nucleic acid for increasing the expression of an encoded peptide or protein is provided. Methods are provided for increasing the expression of a peptide or protein comprising a therapeutic protein or a fragment, variant or derivative thereof. |
Inventor(s): | Thess; Andreas (Kusterdingen, DE), Schlake; Thomas (Gundelfingen, DE), Probst; Jochen (Wolfschlugen, DE) |
Assignee: | CureVac AG (Tubingen, DE) |
Application Number: | 15/899,326 |
Patent Claims: | see list of patent claims |
Details for Patent 10,610,605
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Bristol-myers Squibb Company | YERVOY | ipilimumab | Injection | 125377 | 03/25/2011 | ⤷ Try a Trial | 2032-02-15 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |