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Last Updated: April 26, 2024

Patent: 10,610,605


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Summary for Patent: 10,610,605
Title:Nucleic acid comprising or coding for a histone stem-loop and a poly(A) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein
Abstract: Provided herein are nucleic acid sequences, comprising or coding for a coding region, encoding at least one peptide or protein comprising a therapeutic protein or a fragment, variant or derivative thereof. Furthermore the use of the nucleic acid for increasing the expression of an encoded peptide or protein is provided. Methods are provided for increasing the expression of a peptide or protein comprising a therapeutic protein or a fragment, variant or derivative thereof.
Inventor(s): Thess; Andreas (Kusterdingen, DE), Schlake; Thomas (Gundelfingen, DE), Probst; Jochen (Wolfschlugen, DE)
Assignee: CureVac AG (Tubingen, DE)
Application Number:15/899,326
Patent Claims:see list of patent claims

Details for Patent 10,610,605

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Bristol-myers Squibb Company YERVOY ipilimumab Injection 125377 03/25/2011 ⤷  Try a Trial 2032-02-15
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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