Patent: 9,803,211
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Summary for Patent: 9,803,211
Title: | Protein production in transgenic potato plants having suppressed expression of patatin and CD4B |
Abstract: | The present disclosure relates to methods and constructs for producing heterologous peptides and proteins in plants in a safe and controlled manner. One aspect of the present invention provides a method of producing heterologous protein in a transformed potato plant using an expression cassette comprising a gene coding for a protein or peptide of interest and a marker gene, a nucleotide sequence capable of suppressing patatin expression, along with a nucleotide sequence capable of suppressing CD4B expression, and/or a nucleotide sequence capable of overexpressing P19. Another aspect of the invention provides a method of producing a heterologous protein in a transformed potato plant using an expression cassette comprising a gene coding for a protein or peptide of interest, a marker gene, a transit peptide sequence, and a nucleotide sequence capable of suppressing ADP glucose pyrophosphorylase expression. |
Inventor(s): | Peet; Richard C. (Washington, DC), Rommens; Caius (Boise, ID), Chretien; Robert (Danville, VA), Yan; Hua (Boise, ID), Osumi; Teruko (Garden City, ID) |
Assignee: | J.R. Simplot Company (Boise, ID) |
Application Number: | 14/897,164 |
Patent Claims: | see list of patent claims |
Details for Patent 9,803,211
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Bavarian Nordic A/s | RABAVERT | rabies vaccine | For Injection | 103334 | 10/20/1997 | ⤷ Try a Trial | 2033-06-14 |
Glaxosmithkline Biologicals | HAVRIX | hepatitis a vaccine inactivated | Injection | 103475 | 02/22/1995 | ⤷ Try a Trial | 2033-06-14 |
Sanofi Pasteur Sa | IMOVAX RABIES | rabies vaccine | For Injection | 103931 | 02/04/2000 | ⤷ Try a Trial | 2033-06-14 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |