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Last Updated: May 28, 2020

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Patent: 9,803,211

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Summary for Patent: 9,803,211
Title:Protein production in transgenic potato plants having suppressed expression of patatin and CD4B
Abstract: The present disclosure relates to methods and constructs for producing heterologous peptides and proteins in plants in a safe and controlled manner. One aspect of the present invention provides a method of producing heterologous protein in a transformed potato plant using an expression cassette comprising a gene coding for a protein or peptide of interest and a marker gene, a nucleotide sequence capable of suppressing patatin expression, along with a nucleotide sequence capable of suppressing CD4B expression, and/or a nucleotide sequence capable of overexpressing P19. Another aspect of the invention provides a method of producing a heterologous protein in a transformed potato plant using an expression cassette comprising a gene coding for a protein or peptide of interest, a marker gene, a transit peptide sequence, and a nucleotide sequence capable of suppressing ADP glucose pyrophosphorylase expression.
Inventor(s): Peet; Richard C. (Washington, DC), Rommens; Caius (Boise, ID), Chretien; Robert (Danville, VA), Yan; Hua (Boise, ID), Osumi; Teruko (Garden City, ID)
Assignee: J.R. Simplot Company (Boise, ID)
Application Number:14/897,164
Patent Claims:see list of patent claims

Details for Patent 9,803,211

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Glaxosmithkline Biologicals Sa HAVRIX hepatitis a vaccine INJECTION, SUSPENSION 103475 1 2007-04-13   Start Trial J.R. Simplot Company (Boise, ID) 2033-06-14 search
Glaxosmithkline Biologicals Sa RABAVERT rabies vaccine KIT 103334 1 2016-12-19   Start Trial J.R. Simplot Company (Boise, ID) 2033-06-14 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 9,803,211

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