Last Updated: June 26, 2026

Patent: 9,803,211

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Summary for Patent: 9,803,211

Title:	Protein production in transgenic potato plants having suppressed expression of patatin and CD4B
Abstract:	The present disclosure relates to methods and constructs for producing heterologous peptides and proteins in plants in a safe and controlled manner. One aspect of the present invention provides a method of producing heterologous protein in a transformed potato plant using an expression cassette comprising a gene coding for a protein or peptide of interest and a marker gene, a nucleotide sequence capable of suppressing patatin expression, along with a nucleotide sequence capable of suppressing CD4B expression, and/or a nucleotide sequence capable of overexpressing P19. Another aspect of the invention provides a method of producing a heterologous protein in a transformed potato plant using an expression cassette comprising a gene coding for a protein or peptide of interest, a marker gene, a transit peptide sequence, and a nucleotide sequence capable of suppressing ADP glucose pyrophosphorylase expression.
Inventor(s):	Peet; Richard C. (Washington, DC), Rommens; Caius (Boise, ID), Chretien; Robert (Danville, VA), Yan; Hua (Boise, ID), Osumi; Teruko (Garden City, ID)
Assignee:	J.R. Simplot Company (Boise, ID)
Application Number:	14/897,164
Patent Claims:	see list of patent claims

Details for Patent 9,803,211

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Bavarian Nordic A/s	RABAVERT	rabies vaccine	For Injection	103334	October 20, 1997	⤷ Start Trial	2034-06-13
Glaxosmithkline Biologicals	HAVRIX	hepatitis a vaccine	Injection	103475	February 22, 1995	⤷ Start Trial	2034-06-13
Sanofi Pasteur Inc.	YF-VAX	yellow fever vaccine	For Injection	103915	December 09, 1999	⤷ Start Trial	2034-06-13
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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