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Generated: July 22, 2019

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Patent: 9,528,099

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Summary for Patent: 9,528,099
Title:Fusion proteins of collagen-binding domain and parathyroid hormone
Abstract: Fusion proteins containing active agonist or antagonist fragments of parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrP) coupled to a collagen-binding domain are presented. The fusion proteins can be used to promote bone growth, to promote hair growth, to prevent cancer metastasis to bone, to promote immune reconstitution with a bone marrow stem cell transplant, to promote mobilization of bone marrow stem cells for collection for autologous stem cell transplant, and to treat renal osteodystrophy. Pharmaceutical agents comprising a collagen-binding polypeptide segment linked to a non-peptidyl PTH/PTHrP receptor agonist or antagonist are also presented.
Inventor(s): Gensure; Robert C. (New York, NY), Sakon; Joshua (Fayetteville, AR), Matsushita; Osamu (Okayama, JP), Ponnapakkam; Tulasi (New York, NY)
Assignee: Ochsner Clinic Foundation (N/A) National University Corporation Kagawa University (JP) The Board of Trustees of the University of Arkansas (N/A)
Application Number:14/743,629
Patent Claims:see list of patent claims

Details for Patent 9,528,099

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Advance Biofactures SANTYL collagenase VIAL 101995 001 1965-06-04 ➤ Try a Free Trial Ochsner Clinic Foundation (N/A) National University Corporation Kagawa University (JP) The Board of Trustees of the University of Arkansas (N/A) ➤ Try a Free Trial RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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International Patent Family for US Patent 9,528,099

Country Patent Number Publication Date
World Intellectual Property Organization (WIPO) 2008124166 Jan 15, 2009
World Intellectual Property Organization (WIPO) 2008124166 Nov 05, 2009
World Intellectual Property Organization (WIPO) 2008124166 Oct 16, 2008
United States of America 10202434 Feb 12, 2019
United States of America 2010129341 May 27, 2010
United States of America 2013337017 Dec 19, 2013
Country Patent Number Publication Date

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Julphar
Queensland Health
Baxter
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Mallinckrodt
UBS

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