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Last Updated: December 11, 2019

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Patent: 9,528,099

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Summary for Patent: 9,528,099
Title:Fusion proteins of collagen-binding domain and parathyroid hormone
Abstract: Fusion proteins containing active agonist or antagonist fragments of parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrP) coupled to a collagen-binding domain are presented. The fusion proteins can be used to promote bone growth, to promote hair growth, to prevent cancer metastasis to bone, to promote immune reconstitution with a bone marrow stem cell transplant, to promote mobilization of bone marrow stem cells for collection for autologous stem cell transplant, and to treat renal osteodystrophy. Pharmaceutical agents comprising a collagen-binding polypeptide segment linked to a non-peptidyl PTH/PTHrP receptor agonist or antagonist are also presented.
Inventor(s): Gensure; Robert C. (New York, NY), Sakon; Joshua (Fayetteville, AR), Matsushita; Osamu (Okayama, JP), Ponnapakkam; Tulasi (New York, NY)
Assignee: Ochsner Clinic Foundation (N/A) National University Corporation Kagawa University (JP) The Board of Trustees of the University of Arkansas (N/A)
Application Number:14/743,629
Patent Claims:see list of patent claims

Details for Patent 9,528,099

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial Ochsner Clinic Foundation (N/A) National University Corporation Kagawa University (JP) The Board of Trustees of the University of Arkansas (N/A) 2027-04-09 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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