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Last Updated: April 18, 2024

Patent: 9,315,811

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Summary for Patent: 9,315,811

Title:	Methods for modulating kallikrein (KLKB1) expression
Abstract:	Disclosed herein are methods for decreasing kallikrein and treating or preventing inflammatory conditions in an individual in need thereof. Examples of disease conditions that can be ameliorated with the administration of antisense compounds targeted to kallikrein include hereditary angioedema (HAE). Methods for inhibiting kallikrein can also be used as a prophylactic treatment to prevent individuals at risk for developing an inflammatory condition, such as, hereditary angioedema.
Inventor(s):	Bhattacharjee; Gourab (San Diego, CA), Revenko; Alexey (San Diego, CA), MacLeod; Robert A. (San Diego, CA)
Assignee:	Ionis Pharmaceuticals, Inc. (Carlsbad, CA)
Application Number:	14/124,630
Patent Claims:	see list of patent claims

Details for Patent 9,315,811

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Viropharma Biologics Llc	CINRYZE	c1 esterase inhibitor (human)	For Injection	125267	10/10/2008	⤷ Try a Trial	2031-06-10
Takeda Pharmaceuticals U.s.a., Inc.	KALBITOR	ecallantide	Injection	125277	12/01/2009	⤷ Try a Trial	2031-06-10
Csl Behring Gmbh	BERINERT	c1 esterase inhibitor (human)	For Injection	125287	10/09/2009	⤷ Try a Trial	2031-06-10
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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