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Last Updated: December 3, 2021

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Patent: 9,315,811

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Summary for Patent: 9,315,811
Title:Methods for modulating kallikrein (KLKB1) expression
Abstract: Disclosed herein are methods for decreasing kallikrein and treating or preventing inflammatory conditions in an individual in need thereof. Examples of disease conditions that can be ameliorated with the administration of antisense compounds targeted to kallikrein include hereditary angioedema (HAE). Methods for inhibiting kallikrein can also be used as a prophylactic treatment to prevent individuals at risk for developing an inflammatory condition, such as, hereditary angioedema.
Inventor(s): Bhattacharjee; Gourab (San Diego, CA), Revenko; Alexey (San Diego, CA), MacLeod; Robert A. (San Diego, CA)
Assignee: Ionis Pharmaceuticals, Inc. (Carlsbad, CA)
Application Number:14/124,630
Patent Claims:see list of patent claims

Details for Patent 9,315,811

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Viropharma Biologics Llc CINRYZE c1 esterase inhibitor (human) For Injection 125267 2008-10-10 ⤷  Try it Free 2031-06-10
Takeda Pharmaceuticals U.s.a., Inc. KALBITOR ecallantide Injection 125277 2009-12-01 ⤷  Try it Free 2031-06-10
Csl Behring Gmbh BERINERT c1 esterase inhibitor (human) For Injection 125287 2009-10-09 ⤷  Try it Free 2031-06-10
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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