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Last Updated: November 27, 2021

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Patent: 8,420,081

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Summary for Patent: 8,420,081
Title:Antibody formulations and methods of making same
Abstract: The invention provides an aqueous formulation comprising water and a protein, and methods of making the same. The aqueous formulation of the invention may be a high protein formulation and/or may have low levels of conductivity resulting from the low levels of ionic excipients. Also included in the invention are formulations comprising water and proteins having low osmolality.
Inventor(s): Fraunhofer; Wolfgang (Shrewsbury, MA), Bartl; Annika (Ludwigshafen, DE), Krause; Hans-juergen (Grunstadt, DE), Tschoepe; Markus (Hessheim, DE), Kaleta; Katharina (Ludwigshafen, DE)
Assignee: AbbVie, Inc. (North Chicago, IL)
Application Number:12/325,049
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 8,420,081
Patent Claims:see list of patent claims

Details for Patent 8,420,081

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Centocor Ortho Biotech Products, L.p. ORTHOCLONE OKT3 muromanab-cd3 Injection 103463 1992-09-14 ⤷  Try it Free 2027-11-30
Janssen Biotech, Inc. REOPRO abciximab Injection 103575 1994-12-22 ⤷  Try it Free 2027-11-30
Aytu Bioscience, Inc. PROSTASCINT capromab pendetide Injection 103608 1996-10-28 ⤷  Try it Free 2027-11-30
Genentech, Inc. RITUXAN rituximab Injection 103705 1997-11-26 ⤷  Try it Free 2027-11-30
Idec Pharmaceuticals Corp. RITUXAN rituximab Injection 103737 2002-02-19 ⤷  Try it Free 2027-11-30
Hoffmann-la Roche Inc. ZENAPAX daclizumab Injection 103749 1997-12-10 ⤷  Try it Free 2027-11-30
Novartis Pharmaceuticals Corporation SIMULECT basiliximab For Injection 103764 1998-05-12 ⤷  Try it Free 2027-11-30
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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