Patent: 7,951,557
✉ Email this page to a colleague
Summary for Patent: 7,951,557
| Title: | Human lysosomal proteins from plant cell culture |
| Abstract: | A device, system and method for producing glycosylated proteins in plant culture, particularly proteins having a high mannose glycosylation, while targeting such proteins with an ER signal and/or by-passing the Golgi. The invention further relates to vectors and methods for expression and production of enzymatically active high mannose lysosomal enzymes using transgenic plant root, particularly carrot cells. More particularly, the invention relates to host cells, particularly transgenic suspended carrot cells, vectors and methods for high yield expression and production of biologically active high mannose Glucocerebrosidase (GCD). The invention further provides for compositions and methods for the treatment of lysosomal storage diseases. |
| Inventor(s): | Yoseph Shaaltiel, Gideon Baum, Daniel Bartfeld, Sharon Hashmueli, Ayala Lewkowicz |
| Assignee: | Protalix Ltd |
| Application Number: | US11/790,991 |
| Patent Claims: | see list of patent claims |
Details for Patent 7,951,557
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Pfizer Inc. | ELELYSO | taliglucerase alfa | For Injection | 022458 | May 01, 2012 | ⤷ Start Trial | 2027-04-30 |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
International Patent Family for US Patent 7,951,557
| Country | Patent Number | Estimated Expiration |
|---|---|---|
| Austria | E231912 | ⤷ Start Trial |
| Australia | 2004234635 | ⤷ Start Trial |
| Australia | 2005214181 | ⤷ Start Trial |
| Australia | 2008243744 | ⤷ Start Trial |
| Australia | 4318097 | ⤷ Start Trial |
| Brazil | PI0410520 | ⤷ Start Trial |
| Brazil | PI0810003 | ⤷ Start Trial |
| >Country | >Patent Number | >Estimated Expiration |
