Last Updated: November 8, 2026

Patent: 7,625,558

Summary for Patent: 7,625,558

Title:	Compositions and methods of treating tumors
Abstract:	Methods of treating an individual who has an erbB protein mediated tumor is disclosed. Methods of preventing erbB protein mediated tumors in an individual are disclosed. The methods comprise adminstering to the individual a nucleic acid molecule that encodes a protein that dimerizes with an erbB protein and that is deficient in tyrosine kinase activity. Composition that comprise such nucleic acid molecules including pharmaceutical compositions are disclosed.
Inventor(s):	Mark I. Greene, Donald M. O'Rourke, Ramachandran Murali, Byeong-Woo Park
Assignee:	University of Pennsylvania Penn
Application Number:	US10/100,952
Patent Claims:	see list of patent claims

Details for Patent 7,625,558

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Imclone Llc A Wholly-owned Subsidiary Of Eli Lilly And Company	ERBITUX	cetuximab	Injection	125084	February 12, 2004	⤷ Start Trial	2022-03-19
Imclone Llc A Wholly-owned Subsidiary Of Eli Lilly And Company	ERBITUX	cetuximab	Injection	125084	March 28, 2007	⤷ Start Trial	2022-03-19
Genentech, Inc.	PERJETA	pertuzumab	Injection	125409	June 8, 2012	⤷ Start Trial	2022-03-19
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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