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Last Updated: October 2, 2023

Patent: 7,173,016

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Summary for Patent: 7,173,016

Title:	Composition and method for treating graft-versus-host disease
Abstract:	Compositions and methods are provided for prevention and clinical treatment of various forms of graft-versus-host disease (GVHD) by using inhibitors of adenosine deaminase (ADA). In particular, various formulations and dosing regimens of ADA inhibitors such as pentostatin are provided for the treatment of all forms of GVHD, especially steroid-refractory acute and chronic GVHD.
Inventor(s):	DiMartino; Jorge (San Carlos, CA), Nelson; John Tippett (Danville, CA)
Assignee:	Mayne Pharma (USA) Inc. (Paramus, NJ)
Application Number:	11/208,046
Patent Claims:	see list of patent claims

Details for Patent 7,173,016

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Hoffmann-la Roche Inc.	ZENAPAX	daclizumab	Injection	103749	12/10/1997	⤷ Try a Trial	2021-10-12
Biogen Inc.	ZINBRYTA	daclizumab	Injection	761029	05/27/2016	⤷ Try a Trial	2021-10-12
Biogen Inc.	ZINBRYTA	daclizumab	Injection	761029	05/26/2017	⤷ Try a Trial	2021-10-12
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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