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Last Updated: April 18, 2024

Patent: 7,070,959

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Summary for Patent: 7,070,959

Title:	Modified chimeric polypeptides with improved pharmacokinetic properties
Abstract:	Modified chimeric polypeptides with improved pharmacokinetics are disclosed. Specifically, modified chimeric Flt1 receptor polypeptides that have been modified in such a way as to improve their pharmacokinetic profile are disclosed. Also disclosed are methods of making and using the modified polypeptides including but not limited to using the modified polypeptides to decrease or inhibit plasma leakage and/or vascular permeability in a mammal.
Inventor(s):	Papadopoulos; Nicholas J. (Lagrangeville, NY), Davis; Samuel (New York, NY), Yancopoulos; George D. (Yorktown Heights, NY)
Assignee:	Regeneron Pharmaceuticals, Inc. (Tarrytown, NY)
Application Number:	10/009,852
Patent Claims:	see list of patent claims

Details for Patent 7,070,959

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Regeneron Pharmaceuticals, Inc.	EYLEA	aflibercept	Injection	125387	11/18/2011	⤷ Try a Trial	2019-06-08
Regeneron Pharmaceuticals, Inc.	EYLEA	aflibercept	Injection	125387	08/16/2018	⤷ Try a Trial	2019-06-08
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 7,070,959

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Country	Patent Number	Estimated Expiration
Argentina	044938	⤷ Try a Trial
Austria	293164	⤷ Try a Trial
Austria	417928	⤷ Try a Trial
Austria	427962	⤷ Try a Trial
Austria	486091	⤷ Try a Trial
Australia	2004252175	⤷ Try a Trial
Australia	2005201365	⤷ Try a Trial
>Country	>Patent Number	>Estimated Expiration

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