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Last Updated: October 4, 2024

Patent: 6,627,615


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Summary for Patent: 6,627,615
Title: Methods and compositions for in vivo gene therapy
Abstract:Novel methods and compositions are provided for introducing a gene capable of modulating the genotype and phenotype into two or more tissues following systemic administration. The gene can be introduced into a mammalian host by way of an expression vector either as naked DNA or associated with lipid carriers, particularly cationic lipid carriers. Multiple individual tisssues can be transfected using naked DNA. Using a DNA: lipid carrier complex. multiple tissues and cell types can be transfected. The techniques and compositions find use in the palliation or treatment of any of a variety of genetic-based disorders.
Inventor(s): Debs; Robert J. (Mill Valley, CA), Zhu; Ning (El Cerrito, CA)
Assignee: The Regents of the University of California (Oakland, CA)
Application Number:09/132,391
Patent Claims:see list of patent claims

Details for Patent 6,627,615

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Llc INTRON A interferon alfa-2b For Injection 103132 June 04, 1986 ⤷  Sign Up 2011-12-17
Merck Sharp & Dohme Llc INTRON A interferon alfa-2b For Injection 103132 ⤷  Sign Up 2011-12-17
Merck Sharp & Dohme Llc INTRON A interferon alfa-2b Injection 103132 ⤷  Sign Up 2011-12-17
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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