Last Updated: November 8, 2026

Patent: 6,264,957

Summary for Patent: 6,264,957

Title:	Product of infectious respiratory syncytial virus from cloned nucleotide sequences
Abstract:	Isolated polynucleotide molecules provide RSV genome and antigenomes, including that of human, bovine or murine RSV or RSV-like viruses, and chimera thereof. The recombinant genome or antigenome can be expressed with a nucleocapsid (N) protein, a nucleocapsid phosphoprotein (P), a large (L) polymerase protein, and an RNA polymerase elongation factor to produce isolated infectious RSV particles. The recombinant RSV genome and antigenome can be modified to produce desired phenotypic changes, such as attenuated viruses for vaccine use.
Inventor(s):	Peter L. Collins
Assignee:	HEALTH DEPARTMENT OF United States, , US Department of Health and Human Services
Application Number:	US08/720,132
Patent Claims:	see list of patent claims

Details for Patent 6,264,957

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Llc	ZOSTAVAX	zoster vaccine live	For Injection	125123	May 25, 2006	⤷ Start Trial	2016-09-27
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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