Last Updated: July 4, 2026

Patent: 6,129,913

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Summary for Patent: 6,129,913

Title:	Recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders
Abstract:	Chimeric, humanized and other IL-5 mAbs, derived from high affinity neutralizing mAbs, pharmaceutical compositions containing same, methods of treatment and diagnostics are provided.
Inventor(s):	Robert S. Ames, Edward Robert Appelbaum, Irwin M. Chaiken, Richard M. Cook, Mitchell Stuart Gross, Stephen Dudley Holmes, Lynette Jane McMillan, Timothy Wayne Theisen
Assignee:	SmithKline Beecham Ltd , GlaxoSmithKline LLC
Application Number:	US08/637,647
Patent Claims:	see list of patent claims

Details for Patent 6,129,913

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Glaxosmithkline Llc	NUCALA	mepolizumab	For Injection	125526	November 04, 2015	⤷ Start Trial	2015-12-22
Glaxosmithkline Llc	NUCALA	mepolizumab	Injection	125526	June 06, 2019	⤷ Start Trial	2015-12-22
Glaxosmithkline Llc	NUCALA	mepolizumab	Injection	125526	January 22, 2022	⤷ Start Trial	2015-12-22
Glaxosmithkline Llc	NUCALA	mepolizumab	For Injection	761122	June 06, 2019	⤷ Start Trial	2015-12-22
Glaxosmithkline Llc	NUCALA	mepolizumab	Injection	761122	June 06, 2019	⤷ Start Trial	2015-12-22
Glaxosmithkline Llc	NUCALA	mepolizumab	Injection	761122	January 22, 2022	⤷ Start Trial	2015-12-22
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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