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Last Updated: April 26, 2024

Patent: 6,090,777


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Summary for Patent: 6,090,777
Title: Method to reduce myocardial injury during acute myocardial infarction
Abstract:A therapeutic or prophylactic treatment method of acute myocardial infarction, comprising administering exogenous C1-esterase inhibitor, alone or in combination with other drugs, to a patient with acute myocardial infarction or to a patient at risk for acute myocardial infarction. The treatment inhibits the inflammatory reaction, more specifically the activation of the complement system, which occurs in the course of acute myocardial infarction. The C1-esterase inhibitor may include C1-esterase inhibitor purified from plasma or other biological materials, or recombinant C1-esterase inhibitor, or recombinant variants derived therefrom, or recombinant constructs of other inhibitors having a specificity similar to C1-esterase inhibitor.
Inventor(s): Hack; Cornelis Erik (Diemen, NL), Hermens; Willem Theodoor (Gronsveld, NL)
Assignee: Stiching Centraal Laboratorium Van de Bloedtransfusiedienst Van Het (Amsterdam, NL)
Application Number:08/604,933
Patent Claims:see list of patent claims

Details for Patent 6,090,777

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Microbix Biosystems Inc. KINLYTIC urokinase For Injection 021846 01/16/1978 ⤷  Try a Trial 2013-09-01
Pharming Americas Bv RUCONEST c1 esterase inhibitor (recombinant) For Injection 125495 07/16/2014 ⤷  Try a Trial 2013-09-01
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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