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Last Updated: December 5, 2021

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Patent: 5,843,705

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Summary for Patent: 5,843,705
Title: Transgenically produced antithrombin III
Abstract:This invention relates to transgenically produced human Antithrombin III (tgATIII). The human ATIII produced by the transgenic process of the present invention has a monosaccharide composition which comprises N-acetylgalactosamine (GaINAc) along with fucose, N-acetylglucosamine, galactose, mannose, and N-acetylneuraminic acid/N-glycolyneuraminic acid. The monosaccharide composition differs with that of plasma derived ATIII (phATIII). It has been found that tgATIII has an increased clearance rate when compared to phATIII.
Inventor(s): DiTullio; Paul (Framingham, MA), Meade; Harry (Newton, MA), Cole; Edward S. (Mendon, MA)
Assignee: Genzyme Transgenic Corporation (Framingham, MA)
Application Number:08/391,743
Patent Claims:see list of patent claims

Details for Patent 5,843,705

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Grifols Therapeutics Llc THROMBATE III antithrombin iii (human) For Injection 103196 1991-12-30 ⤷  Try it Free 2040-01-28
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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