Patent: 5,716,824
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Summary for Patent: 5,716,824
| Title: | 2\'-O-alkylthioalkyl and 2-C-alkylthioalkyl-containing enzymatic nucleic acids (ribozymes) |
| Abstract: | A compound having the formula: ##STR1## wherein, R1 represents 2\'-O-R.sub.3 -thio-R.sub.3 and/or 2\'-C-R.sub.3 -thio-R.sub.3, wherein R.sub.3 is independently a moiety selected from a group consisting of alkyl, alkenyl, alkynyl, aryl, alkylaryl, carbocyclic aryl, heterocyclic aryl, amide and ester, X represents a base or H; Y represents a phosphorus-containing group; and R2 represents H, DMT or a phosphorus-containing group. |
| Inventor(s): | Beigelman; Leonid (Longmont, CO), Karpeisky; Alex (Boulder, CO) |
| Assignee: | Ribozyme Pharmaceuticals, Inc. (Boulder, CO) |
| Application Number: | 08/426,124 |
| Patent Claims: | see list of patent claims |
Details for Patent 5,716,824
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | For Injection | 103132 | 06/04/1986 | See Plans and Pricing | 2039-02-26 |
| Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | For Injection | 103132 | See Plans and Pricing | 2039-02-26 | |
| Merck Sharp & Dohme Corp. | INTRON A | interferon alfa-2b | Injection | 103132 | See Plans and Pricing | 2039-02-26 | |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
