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Last Updated: April 23, 2024

Patent: 5,051,408


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Summary for Patent: 5,051,408
Title: Inulin compositions in gamma polymorphic form
Abstract:A process for preparing gamma inulin comprising the steps of (a) recrystallizing crude inulin from water at a temperature below 37.degree. C. to obtain a suspension, (b) heating the suspension at a temperature of from about 25.degree. to 45.degree. C. for about 1-3 days, (c) further heating the suspension at a temperature of about 40.degree. to 55.degree. C. for about 0.5 to 1.5 hours, and (d) isolating insoluble gamma inulin from the suspension. A composition comprising particles of inulin or an inulin derivative in the gamma polymorphic form is characterized in that the particles have a low rate of solution in aqueous media above 30.degree. C., particularly above 37.degree. C. The composition is effective as the active component of an immunotherapeutic preparation for activation of the alternative pathway of complement, or for antitumor treatment.
Inventor(s): Cooper; Peter Dodd (Monash, AU)
Assignee: The Australian National University (Acton, AU)
Application Number:07/501,752
Patent Claims:see list of patent claims

Details for Patent 5,051,408

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Grifols Therapeutics Llc BAYGAM, GAMASTAN S/D immune globulin (human) Injection 101134 01/11/1944 ⤷  Try a Trial 2008-09-24
Grifols Therapeutics Llc GAMMAKED (KENDRION), GAMUNEX-C immune globulin injection (human) 10% caprylate/chromatography purified Injection 125046 08/27/2003 ⤷  Try a Trial 2008-09-24
Octapharma Pharmazeutika Produktionsges.m.b.h. OCTAGAM immune globulin intravenous (human) Injection 125062 05/21/2004 ⤷  Try a Trial 2008-09-24
Octapharma Pharmazeutika Produktionsges.m.b.h. OCTAGAM immune globulin intravenous (human) Injection 125062 03/26/2007 ⤷  Try a Trial 2008-09-24
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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