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Last Updated: September 27, 2020

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Patent: 4,391,746

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Summary for Patent: 4,391,746
Title: Blood-coagulation-promoting products and methods of preparing them
Abstract:Blood-coagulation-promoting products substantially free of thrombin are prepared from human blood plasma by contacting a human blood plasma fraction containing coagulation Factors II, VII, IX and X with an anion exchanger to adsorb the coagulation Factors, which are subsequently eluted from the anion exchanger. The eluate is treated to generate a substance having Factor VIII Inhibitor Bypassing Activity and being substantially free of thrombin, and activated Factor X.
Inventor(s): Mitra; Gautam (Kensington, CA), Coan; Michael H. (El Cerrito, CA), Wada; Shohachi (Oakland, CA)
Assignee: Cutter Laboratories, Inc. (Berkeley, CA)
Application Number:06/374,835
Patent Claims:see list of patent claims

Details for Patent 4,391,746

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Baxalta Incorporated FEIBA anti-inhibitor coagulant complex KIT 101447 1 1986-01-31   Start Trial Cutter Laboratories, Inc. (Berkeley, CA) 2000-07-05 search
Ethicon, Inc THROMBIN HUMAN thrombin human POWDER, FOR SOLUTION 125247 1 2009-09-19   Start Trial Cutter Laboratories, Inc. (Berkeley, CA) 2000-07-05 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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