Patent: 4,387,092
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Summary for Patent: 4,387,092
| Title: | Process for the preparation of factor VIII concentrate |
| Abstract: | An improved process for preparing factor VIII concentrate which comprises a first stage wherein fibrinogen is precipitated from a buffered plasma or plasma cryoprecipitate solution by the addition of a polyol and a second stage where factor VIII is precipitated from the resulting supernatant also by the addition of a polyol. The improvement in the first stage resides in adding the polyol in an amount of 1-3% and maintaining the temperature of the buffered solution between about 2°-4° C. |
| Inventor(s): | Jacques Liautaud, Edward Shanbrom |
| Assignee: | Institut Merieux SA , LOreal SA |
| Application Number: | US06/237,135 |
| Patent Claims: | see list of patent claims |
Details for Patent 4,387,092
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Csl Behring Llc | MONOCLATE, MONOCLATE-P | antihemophilic factor (human) | For Injection | 103953 | 14-May-03 | ⤷ Start Trial | 2000-06-30 |
| Csl Behring Llc | MONOCLATE, MONOCLATE-P | antihemophilic factor (human) | For Injection | 103953 | 4-Mar-04 | ⤷ Start Trial | 2000-06-30 |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
