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Last Updated: March 29, 2024

Patent: 4,364,861


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Summary for Patent: 4,364,861
Title: Blood-coagulation-promoting products and methods of preparing them
Abstract:Blood-coagulation-promoting products substantially free of thrombin are prepared from human blood plasma by contacting a human blood plasma fraction containing coagulation Factors II, VII, IX and X with an anion exchanger to adsorb the coagulation Factors, which are subsequently eluted from the anion exchanger. The eluate is treated to generate a substance having Factor VIII Inhibitor Bypassing Activity and being substantially free of thrombin, and activated Factor X.
Inventor(s): Mitra; Gautam (Kensington, CA), Coan; Michael H. (El Cerrito, CA), Wada; Shohachi (Oakland, CA)
Assignee: Cutter Laboratories, Inc. (Berkeley, CA)
Application Number:06/153,341
Patent Claims:see list of patent claims

Details for Patent 4,364,861

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Baxalta Us Inc. AUTOPLEX, FEIBA NF, FEIBA VH anti-inhibitor coagulant complex For Injection 101447 12/21/1979 ⤷  Try a Trial 2040-01-28
Baxalta Us Inc. AUTOPLEX, FEIBA NF, FEIBA VH anti-inhibitor coagulant complex For Injection 101447 07/31/2000 ⤷  Try a Trial 2040-01-28
Baxalta Us Inc. AUTOPLEX, FEIBA NF, FEIBA VH anti-inhibitor coagulant complex For Injection 101447 08/11/2005 ⤷  Try a Trial 2040-01-28
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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